smiles stringlengths 2 611 | question_style stringclasses 4
values | question stringlengths 65 683 | options listlengths 4 4 | answer stringclasses 4
values | difficulty_tier stringclasses 3
values | question_variant stringclasses 2
values |
|---|---|---|---|---|---|---|
Brc1cccc2c(-c3ccccc3)c3c(c(-c4ccccc4)c12)-c1cccc2cccc-3c12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cccc2c(-c3ccccc3)c3c(c(-c4ccccc4)c12)-c1cccc2cccc-3c12: bromoalkene, bromoformate, and difluoromethyl? | [
"1",
"2",
"0",
"3"
] | C | easy | decoy |
Brc1cccc2c3c4oc5ccccc5c4ccc3n(-c3ccccc3)c12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cccc2c3c4oc5ccccc5c4ccc3n(-c3ccccc3)c12: bromoalkene, difluoromethyl, and trifluoromethyl? | [
"0",
"2",
"3",
"1"
] | A | easy | decoy |
Brc1cccc2cc(-c3ccccc3)oc12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cccc2cc(-c3ccccc3)oc12: chloride, difluoromethyl, and trifluoromethyl? | [
"0",
"3",
"2",
"1"
] | A | easy | decoy |
Brc1cccc2nc(C#Cc3cccnc3)ccc12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cccc2nc(C#Cc3cccnc3)ccc12: aryl chloride, aryl fluoride, and primary amine? | [
"0",
"2",
"1",
"3"
] | A | easy | decoy |
Brc1cccc2nsnc12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cccc2nsnc12: aryl fluoride, chloride, and iodide? | [
"0",
"2",
"1",
"3"
] | A | easy | decoy |
Brc1ccccc1-c1ccc2c(c1)ncc1cccnc12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1ccccc1-c1ccc2c(c1)ncc1cccnc12: chloride, difluoromethyl, and iodide? | [
"2",
"3",
"0",
"1"
] | C | easy | decoy |
Brc1ccccc1-c1cccc(N(c2ccccc2)c2cccc(-c3ccccc3-c3ccccc3)c2)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1ccccc1-c1cccc(N(c2ccccc2)c2cccc(-c3ccccc3-c3ccccc3)c2)c1: chloride, enamine, and iodide? | [
"0",
"3",
"1",
"2"
] | A | easy | decoy |
Brc1ccccc1CN1CCN(c2nnc(Nc3ccc(N4CCOCC4)cc3)c3ccccc23)CC1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1ccccc1CN1CCN(c2nnc(Nc3ccc(N4CCOCC4)cc3)c3ccccc23)CC1: amidrazone, bromoalkene, and primary amine? | [
"3",
"0",
"1",
"2"
] | B | easy | decoy |
Brc1ccccc1SC1CN2CCC1CC2 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1ccccc1SC1CN2CCC1CC2: primary amine, secondary amine, and thioaldehyde? | [
"1",
"3",
"2",
"0"
] | D | easy | decoy |
Brc1ccn2ncnc(NC3=NC[C@@]4(CN5CCC4CC5)O3)c12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1ccn2ncnc(NC3=NC[C@@]4(CN5CCC4CC5)O3)c12: guanidine, isothiourea, and primary amine? | [
"3",
"1",
"2",
"0"
] | D | easy | decoy |
Brc1cn2ccnc2c(Br)n1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cn2ccnc2c(Br)n1: aryl chloride, aryl fluoride, and bromoformate? | [
"2",
"3",
"1",
"0"
] | D | easy | decoy |
Brc1cnc(-c2cc3ccccc3o2)c2nsnc12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cnc(-c2cc3ccccc3o2)c2nsnc12: bromoalkene, bromoformate, and difluoromethyl? | [
"1",
"3",
"2",
"0"
] | D | easy | decoy |
Brc1cnc2[nH]c(-c3ccc(OCCN4CCCCC4)cc3)nc2c1NCCC1CCNCC1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cnc2[nH]c(-c3ccc(OCCN4CCCCC4)cc3)nc2c1NCCC1CCNCC1: aryl chloride, bromoformate, and hydroperoxide? | [
"1",
"2",
"3",
"0"
] | D | easy | decoy |
Brc1cnc2[nH]ccc2n1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cnc2[nH]ccc2n1: bromoalkene, bromoformate, and difluoromethyl? | [
"0",
"2",
"3",
"1"
] | A | easy | decoy |
Brc1cnc2cn[nH]c2c1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cnc2cn[nH]c2c1: aryl fluoride, chloride, and iodide? | [
"1",
"3",
"0",
"2"
] | C | easy | decoy |
Brc1cnc2nc3ccc4ccc(C5=NCCN5)cc4n3c2c1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cnc2nc3ccc4ccc(C5=NCCN5)cc4n3c2c1: aryl chloride, aryl iodide, and hydrazone? | [
"3",
"0",
"2",
"1"
] | B | easy | decoy |
Brc1cncc(-c2ccsc2)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cncc(-c2ccsc2)c1: aryl chloride, aryl fluoride, and aryl iodide? | [
"2",
"3",
"0",
"1"
] | C | easy | decoy |
Brc1cncc(C2CN3CCC2CC3)n1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cncc(C2CN3CCC2CC3)n1: amidine, difluoromethyl, and trifluoromethyl? | [
"0",
"1",
"3",
"2"
] | A | easy | decoy |
Brc1cncc(N2CC3CC(C2)N3)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cncc(N2CC3CC(C2)N3)c1: azine, difluoromethyl, and hydrazine? | [
"1",
"0",
"2",
"3"
] | B | easy | decoy |
Brc1cncc(N2C[C@H]3CN[C@H]3C2)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cncc(N2C[C@H]3CN[C@H]3C2)c1: aryl chloride, aryl fluoride, and carbodiimide? | [
"2",
"3",
"0",
"1"
] | C | easy | decoy |
Brc1cncc2nccn12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cncc2nccn12: bromoalkene, difluoromethyl, and trifluoromethyl? | [
"0",
"2",
"1",
"3"
] | A | easy | decoy |
Brc1cncnc1-c1ccco1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cncnc1-c1ccco1: bromoalkene, difluoromethyl, and trifluoromethyl? | [
"3",
"2",
"0",
"1"
] | C | easy | decoy |
Brc1cnn2c(NCc3cccnc3)cc(N3CCNCC3)nc12 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1cnn2c(NCc3cccnc3)cc(N3CCNCC3)nc12: amidrazone, bromoalkene, and enamine? | [
"2",
"3",
"0",
"1"
] | C | easy | decoy |
Brc1coc(C2=CN3CCC2CC3)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1coc(C2=CN3CCC2CC3)c1: bromoalkene, bromoformate, and carbodiimide? | [
"1",
"3",
"0",
"2"
] | C | easy | decoy |
Brc1csnc1CO[C@@H]1CCC12CCNCC2 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1csnc1CO[C@@H]1CCC12CCNCC2: aryl chloride, aryl fluoride, and ortho ester? | [
"0",
"1",
"2",
"3"
] | A | easy | decoy |
Brc1nc(C23CC4CC(CC(C4)C2)C3)co1 | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1nc(C23CC4CC(CC(C4)C2)C3)co1: difluoromethyl, fluoride, and trifluoromethyl? | [
"3",
"0",
"1",
"2"
] | B | easy | decoy |
Brc1nc(N2CCN([C@@H]3CCNC3)CC2)sc1Br | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1nc(N2CCN([C@@H]3CCNC3)CC2)sc1Br: amidrazone, bromoalkene, and guanidine? | [
"0",
"3",
"2",
"1"
] | A | easy | decoy |
Brc1oc2ccncc2c1Br | count_present | How many of the following functional groups are present in the molecule with SMILES Brc1oc2ccncc2c1Br: bromoalkene, difluoromethyl, and trifluoromethyl? | [
"3",
"2",
"0",
"1"
] | C | easy | decoy |
C#C/C(O)=C(O)\C(O)=C(\O)CN(c1cc2c(c3ccccc13)-c1cc3c(cc1C2(C)C)-c1ccc(N(c2c(O)c(O)c(O)c(O)c2O)c2c(O)c(O)c(O)c(O)c2O)cc1C3(C)C)C1C(O)=C(O)C(O)=C1O | count_present | How many of the following functional groups are present in the molecule with SMILES C#C/C(O)=C(O)\C(O)=C(\O)CN(c1cc2c(c3ccccc13)-c1cc3c(cc1C2(C)C)-c1ccc(N(c2c(O)c(O)c(O)c(O)c2O)c2c(O)c(O)c(O)c(O)c2O)cc1C3(C)C)C1C(O)=C(O)C(O)=C1O: primary amine, thioaldehyde, and thiocarbonic acid diester? | [
"2",
"3",
"1",
"0"
] | D | easy | decoy |
C#C/C=C(\c1ccc(N(C)C)cc1)c1ccc2nc(N)n(S(=O)(=O)C(C)C)c2c1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#C/C=C(\c1ccc(N(C)C)cc1)c1ccc2nc(N)n(S(=O)(=O)C(C)C)c2c1: sulfilimine, sulfonic halide, and sulfuric esteramide? | [
"3",
"1",
"2",
"0"
] | D | easy | decoy |
C#C/C=C\c1c(C)c(-c2ccc3sc4c(-c5c6ccccc6c(-c6ccc(-c7ccccc7)c7ccccc67)c6ccccc56)cccc4c3c2)c2ccccc2c1-c1ccccc1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#C/C=C\c1c(C)c(-c2ccc3sc4c(-c5c6ccccc6c(-c6ccc(-c7ccccc7)c7ccccc67)c6ccccc56)cccc4c3c2)c2ccccc2c1-c1ccccc1: aldehyde, primary amine, and sulfilimine? | [
"0",
"3",
"1",
"2"
] | A | easy | decoy |
C#CC#CC#C/C=C/C=C/C(C)O | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#C/C=C/C=C/C(C)O: hemiketal, ortho ester, and thioarene? | [
"1",
"2",
"3",
"0"
] | D | easy | decoy |
C#CC#CC#C/C=C/CO | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#C/C=C/CO: hydrazine, hydrazone, and ortho ester? | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC: alkene, thioaldehyde, and thiocyanate? | [
"3",
"2",
"1",
"0"
] | D | easy | decoy |
C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#C[Si](C)(O[Si](C)(C)C)O[Si](C)(CC[Si](C)(C)O[Si](C)(C)C)O[Si](C)(C#CC#CC#C)O[Si](C)(C)C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#C[Si](C)(O[Si](C)(C)C)O[Si](C)(CC[Si](C)(C)O[Si](C)(C)C)O[Si](C)(C#CC#CC#C)O[Si](C)(C)C: carboxylic ester, hydrazine, and thioarene? | [
"3",
"2",
"1",
"0"
] | D | easy | decoy |
C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#COC(=O)C(=C)C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#COC(=O)C(=C)C: bromoalkene, hydroxylamine, and sulfinic ester? | [
"2",
"1",
"0",
"3"
] | C | easy | decoy |
C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#COc1cc(COc2ccc3cc(COC(=O)CCC(=O)O[C@H]4C[C@@H](COP(=O)(OCCC#N)OC5C[C@H](n6cc(C)c(=O)[nH]c6=O)O[C@@H]5CC)O[C@H]4n4cc(C)c(=O)[nH]c4=O)ccc3c2)cc(OC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#C)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#COc1cc(COc2ccc3cc(COC(=O)CCC(=O)O[C@H]4C[C@@H](COP(=O)(OCCC#N)OC5C[C@H](n6cc(C)c(=O)[nH]c6=O)O[C@@H]5CC)O[C@H]4n4cc(C)c(=O)[nH]c4=O)ccc3c2)cc(OC#CC#CC#CC#CC#CC#CC#CC#CC#CC#CC#C)c1: acyl azide, hydroxamic ... | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC#CC#CC#CC#CC#CC#CC(=O)OC[C@H](COP(=O)(O)OC1C(O)[C@H](OP(=O)(O)O)[C@H](CP(=O)(O)O)C(O)[C@@H]1O)OC(=O)CCCCCCCCCCCCCCC | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#CC#CC#CC#CC#CC(=O)OC[C@H](COP(=O)(O)OC1C(O)[C@H](OP(=O)(O)O)[C@H](CP(=O)(O)O)C(O)[C@@H]1O)OC(=O)CCCCCCCCCCCCCCC: phosphonic esteramide, phosphoric monoesterdiamide, and phosphoric monoestermonoamide? | [
"1",
"3",
"0",
"2"
] | C | easy | decoy |
C#CC#CC#CC#CC#CC(=O)OC[C@H](COP(=O)(O)OC1C(O)[C@H](OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)[C@@H]1O)OC(=O)CCCCCCCCCCCCCCC | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#CC#CC#CC(=O)OC[C@H](COP(=O)(O)OC1C(O)[C@H](OP(=O)(O)O)C(OP(=O)(O)O)C(OP(=O)(O)O)[C@@H]1O)OC(=O)CCCCCCCCCCCCCCC: hemiketal, hydrazine, and thioarene? | [
"0",
"2",
"3",
"1"
] | A | easy | decoy |
C#CC#CC#CC#Cc1c(-c2ccc(-c3ccc(C)s3)s2)sc(-c2ccc(-c3ccc(-c4ccc5c(c4)C(CCCCCCCC)(CCCCCCCC)c4cc(-c6ccc(C)s6)ccc4-5)s3)s2)c1CCCCCCCC | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC#CC#Cc1c(-c2ccc(-c3ccc(C)s3)s2)sc(-c2ccc(-c3ccc(-c4ccc5c(c4)C(CCCCCCCC)(CCCCCCCC)c4cc(-c6ccc(C)s6)ccc4-5)s3)s2)c1CCCCCCCC: hydrazine, primary amine, and thioarene? | [
"1",
"3",
"2",
"0"
] | D | easy | decoy |
C#CC#CC1=CC(=O)C[C@@H]1O | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC1=CC(=O)C[C@@H]1O: carbonic acid diester, carboxylic anhydride, and hemiacetal? | [
"1",
"3",
"0",
"2"
] | C | easy | decoy |
C#CC#CC=C=CCO | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC#CC=C=CCO: hydroperoxide, ketenacetal, and thioaldehyde? | [
"2",
"1",
"0",
"3"
] | C | easy | decoy |
C#CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c2)CC1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(=O)N1CCN(c2ccc([N+](=O)[O-])c(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c2)CC1: acyl azide, bromoalkene, and isocyanate? | [
"1",
"0",
"3",
"2"
] | B | easy | decoy |
C#CC(=O)NC(NC(=O)C#C)C(=O)N(CCC(=O)N(CCC(=O)ON1COCCCC1=O)CCC(=O)ON1C(=O)CCC1=O)CCC(=O)N(CCC(=O)ON1C(=O)CCC1=O)CCC(=O)ON1C(=O)CCC1=O | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(=O)NC(NC(=O)C#C)C(=O)N(CCC(=O)N(CCC(=O)ON1COCCCC1=O)CCC(=O)ON1C(=O)CCC1=O)CCC(=O)N(CCC(=O)ON1C(=O)CCC1=O)CCC(=O)ON1C(=O)CCC1=O: carbazone, hydrazinecarboxylate, and sulfilimine? | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC(=O)NCCCCCC(=O)NC(COCCC=O)(COCCC(=O)NCCOCCOCCO)COCCC(=O)NCCOCCOCCO[C@@H](OC(CO)[C@H](C)O)[C@H](O)CO | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(=O)NCCCCCC(=O)NC(COCCC=O)(COCCC(=O)NCCOCCOCCO)COCCC(=O)NCCOCCOCCO[C@@H](OC(CO)[C@H](C)O)[C@H](O)CO: carboxylic acid, carboxylic anhydride, and hemiacetal? | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC(=O)c1sc(C)nc1C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(=O)c1sc(C)nc1C: carboxylic acid, carboxylic ester, and thioaldehyde? | [
"1",
"3",
"0",
"2"
] | C | easy | decoy |
C#CC(C)(C)C[C@@H](O)c1csc(C)c1C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(C)(C)C[C@@H](O)c1csc(C)c1C: acetal, imine, and sulfilimine? | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC(C)/C=C(\C=C(\N)OC)Nc1ncc(C(F)(F)F)c(Nc2cc(O)ccc2NC(=O)C=C)n1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(C)/C=C(\C=C(\N)OC)Nc1ncc(C(F)(F)F)c(Nc2cc(O)ccc2NC(=O)C=C)n1: acylhydrazone, dicarbodiazene, and semicarbazone? | [
"2",
"3",
"0",
"1"
] | C | easy | decoy |
C#CC(C)=CC=C(CC)OC(F)(F)c1ccc(Cc2ccc(C(F)(F)Oc3ccc(C#N)cc3)c(F)c2)cc1F | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(C)=CC=C(CC)OC(F)(F)c1ccc(Cc2ccc(C(F)(F)Oc3ccc(C#N)cc3)c(F)c2)cc1F: aryl chloride, carbodiimide, and secondary amine? | [
"2",
"3",
"0",
"1"
] | C | easy | decoy |
C#CC(C)N(C)CC(=C)c1ccccc1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(C)N(C)CC(=C)c1ccccc1: bromoalkene, primary amine, and secondary amine? | [
"1",
"3",
"0",
"2"
] | C | easy | decoy |
C#CC(C)c1ccc(C(=O)OC)s1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(C)c1ccc(C(=O)OC)s1: carbonic acid esterhalide, enolester, and primary amine? | [
"3",
"1",
"2",
"0"
] | D | easy | decoy |
C#CC(CC(=C)C)O[Si](C)(C)C(C)(C)C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC(CC(=C)C)O[Si](C)(C)C(C)(C)C: thioaldehyde, thiocyanate, and thioketone? | [
"2",
"1",
"0",
"3"
] | C | easy | decoy |
C#CC12CC3(C)CC(C)(C1)CC(C14CC5(C)CC(C)(CC(C#C)(C5)C1)C4)(C3)C2 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC12CC3(C)CC(C)(C1)CC(C14CC5(C)CC(C)(CC(C#C)(C5)C1)C4)(C3)C2: nitrile, sulfilimine, and thiocyanate? | [
"2",
"0",
"1",
"3"
] | B | easy | decoy |
C#CC12CC3C4CC5(C67CC8C9CC%10(C%11%12CC%13C%14CC%15(C#C)CC%13C(C%11)C(C%15)C%14C%12)CC8C(C6)C(C%10)C9C7)CC3C(C1)C(C5)C4C2 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC12CC3C4CC5(C67CC8C9CC%10(C%11%12CC%13C%14CC%15(C#C)CC%13C(C%11)C(C%15)C%14C%12)CC8C(C6)C(C%10)C9C7)CC3C(C1)C(C5)C4C2: sulfilimine, thioarene, and thioketone? | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC12CC3C4CC5CC3C(C(C5)C4C1)C2C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC12CC3C4CC5CC3C(C(C5)C4C1)C2C: alkene, ketone, and thioaldehyde? | [
"0",
"3",
"2",
"1"
] | A | easy | decoy |
C#CC12CC3CC4C5CC(CC41)C(C)C2C5C3 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC12CC3CC4C5CC(CC41)C(C)C2C5C3: alkene, ketone, and thioaldehyde? | [
"3",
"2",
"0",
"1"
] | C | easy | decoy |
C#CC12CC3C[C@@H]4[C@H]1CC1C[C@H]2[C@H](C3)C4(C#C)C1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC12CC3C[C@@H]4[C@H]1CC1C[C@H]2[C@H](C3)C4(C#C)C1: hydrazine, thioarene, and thioketone? | [
"1",
"3",
"2",
"0"
] | D | easy | decoy |
C#CC12OC3(O)C4C5CC(C6C5C3(C)C61)C42 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC12OC3(O)C4C5CC(C6C5C3(C)C61)C42: carbonic acid esterhalide, sulfilimine, and thioketone? | [
"1",
"2",
"0",
"3"
] | C | easy | decoy |
C#CC1=C(N)OC(c2ccccc2)=C(C(=O)OCC)C1c1ccc(Cl)s1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC1=C(N)OC(c2ccccc2)=C(C(=O)OCC)C1c1ccc(Cl)s1: carbonic acid diester, ketenacetal, and thioaldehyde? | [
"1",
"2",
"0",
"3"
] | C | easy | decoy |
C#CC1=CCCc2cc(O)cc(-c3ncc4c(N5CC6C[N+]67CC7C5)nc(OCC56CCCN5CCC6)nc4c3F)c21 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC1=CCCc2cc(O)cc(-c3ncc4c(N5CC6C[N+]67CC7C5)nc(OCC56CCCN5CCC6)nc4c3F)c21: acetonide, bromoalkene, and sulfinic ester? | [
"3",
"2",
"1",
"0"
] | D | easy | decoy |
C#CC1C2CC3CC(C2)CC1(C12CC4CC(CC(C4)C1)C2)C3 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC1C2CC3CC(C2)CC1(C12CC4CC(CC(C4)C1)C2)C3: alkene, ketone, and thioaldehyde? | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC1CC(=O)N(C(C)(C)COC)C1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC1CC(=O)N(C(C)(C)COC)C1: carbazide, primary amine, and semicarbazide? | [
"3",
"2",
"1",
"0"
] | D | easy | decoy |
C#CC1CCC(C#N)N1C(=O)C(NC(=O)OC(C)(C)C)C1CC2CCC1N2C(=O)c1ccnc(F)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC1CCC(C#N)N1C(=O)C(NC(=O)OC(C)(C)C)C1CC2CCC1N2C(=O)c1ccnc(F)c1: hydroxamic acid, hydroxamic acid ester, and primary amine? | [
"2",
"0",
"3",
"1"
] | B | easy | decoy |
C#CC1CCN(C(=O)c2cn(-c3ccc4scc(C)c4c3)c(=O)c3cc(OC)c(OC)cc23)CC1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC1CCN(C(=O)c2cn(-c3ccc4scc(C)c4c3)c(=O)c3cc(OC)c(OC)cc23)CC1: acylhydrazone, hydroxamic acid, and hydroxy? | [
"0",
"3",
"1",
"2"
] | A | easy | decoy |
C#CC=CCC1OC2CC1OC2CC(Br)C(Br)CC | count_present | How many of the following functional groups are present in the molecule with SMILES C#CC=CCC1OC2CC1OC2CC(Br)C(Br)CC: bromoalkene, ketenacetal, and thioketone? | [
"0",
"2",
"1",
"3"
] | A | easy | decoy |
C#CCC#CCN/N=C/Cc1ccccc1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC#CCN/N=C/Cc1ccccc1: guanidine, isothiourea, and primary amine? | [
"0",
"2",
"3",
"1"
] | A | easy | decoy |
C#CCC(=O)Cc1cccc(Cl)c1Cl | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC(=O)Cc1cccc(Cl)c1Cl: acyl fluoride, difluoromethyl, and hydroxylamine? | [
"2",
"3",
"1",
"0"
] | D | easy | decoy |
C#CCC(C)N1C(=O)C=C(C)C1=O | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC(C)N1C(=O)C=C(C)C1=O: acylhydrazone, ketenacetal, and thioaldehyde? | [
"2",
"3",
"0",
"1"
] | C | easy | decoy |
C#CCC(C)NCC1CCC(C)O1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC(C)NCC1CCC(C)O1: isothiourea, primary amine, and tertiary amine? | [
"0",
"3",
"2",
"1"
] | A | easy | decoy |
C#CCC(Cc1ccc(F)cc1F)NC | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC(Cc1ccc(F)cc1F)NC: difluoromethyl, primary amine, and trifluoromethyl? | [
"0",
"2",
"3",
"1"
] | A | easy | decoy |
C#CCC1(O)C(C)CC2C3CC=C4CC(=O)CCC4=C3C(c3ccc(N(C)CCOC4CCC5(C)C(C4)CC(OC(=O)OCCN)C4C5CC(O)C5(C)C(C(C)CCC(=O)O)CCC45)cc3)CC21C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC1(O)C(C)CC2C3CC=C4CC(=O)CCC4=C3C(c3ccc(N(C)CCOC4CCC5(C)C(C4)CC(OC(=O)OCCN)C4C5CC(O)C5(C)C(C(C)CCC(=O)O)CCC45)cc3)CC21C: hydrazine, hydroperoxide, and sulfilimine? | [
"2",
"3",
"1",
"0"
] | D | easy | decoy |
C#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(S(=O)(=O)CC)C1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(S(=O)(=O)CC)C1: sulfonic halide, sulfuric esteramide, and thioaldehyde? | [
"2",
"0",
"1",
"3"
] | B | easy | decoy |
C#CCC12c3c4c5c6c7c8c(c9c%10c1c1c3c3c%11c4c4c5c5c7c7c%12c8c8c9c9c%10c%10c1c1c3c3c%11c%11c4c4c5c7c5c7c%12c8c8c9c9c%10c1c1c3c3c%11c4c5c4c7c8c9c1c34)C62 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC12c3c4c5c6c7c8c(c9c%10c1c1c3c3c%11c4c4c5c5c7c7c%12c8c8c9c9c%10c%10c1c1c3c3c%11c%11c4c4c5c7c5c7c%12c8c8c9c9c%10c1c1c3c3c%11c4c5c4c7c8c9c1c34)C62: nitrile, sulfilimine, and thiocyanate? | [
"2",
"3",
"1",
"0"
] | D | easy | decoy |
C#CCC=NC=C(C)C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCC=NC=C(C)C: disulfide, hydroxylamine, and thioaldehyde? | [
"1",
"3",
"0",
"2"
] | C | easy | decoy |
C#CCCC1(CCN2CCN(Cc3cc(NC(=O)c4ccc5c(c4)CN(c4cncnc4)CC5C)cc(C(F)(F)F)c3)CC2)N=N1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCC1(CCN2CCN(Cc3cc(NC(=O)c4ccc5c(c4)CN(c4cncnc4)CC5C)cc(C(F)(F)F)c3)CC2)N=N1: acyl fluoride, hydroxamic acid ester, and semicarbazide? | [
"0",
"3",
"2",
"1"
] | A | easy | decoy |
C#CCCCCCN(C)[C@H]1CC=CCC1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCCCN(C)[C@H]1CC=CCC1: primary amine, thioaldehyde, and thioketone? | [
"3",
"2",
"1",
"0"
] | D | easy | decoy |
C#CCCCCCNC(=O)Nc1nc2nn(C)cc2c2nc(-c3ccco3)nn12 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCCCNC(=O)Nc1nc2nn(C)cc2c2nc(-c3ccco3)nn12: hydroxamic acid ester, semicarbazide, and thiocyanate? | [
"3",
"2",
"0",
"1"
] | C | easy | decoy |
C#CCCCCNC(=O)NC(=N)NCCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)C(C)(C)C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCCNC(=O)NC(=N)NCCC[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)C(C)(C)C: hydroperoxide, hydroxamic acid ester, and semicarbazide? | [
"3",
"2",
"0",
"1"
] | C | easy | decoy |
C#CCCCCOC1=CC(=O)N(C(=O)/C=C/[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)OC(=O)[C@H]([C@@H](C)CC)N(C)C)[C@@H]1C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCCOC1=CC(=O)N(C(=O)/C=C/[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)OC(=O)[C@H]([C@@H](C)CC)N(C)C)[C@@H]1C: dicarbodiazene, hydroxamic acid ester, and thioarene? | [
"0",
"2",
"3",
"1"
] | A | easy | decoy |
C#CCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc1ccc(Br)c(-c2cc3cnc(N)nc3nc2N)c1Br | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOc1ccc(Br)c(-c2cc3cnc(N)nc3nc2N)c1Br: guanidine, hemiacetal, and thioketone? | [
"3",
"1",
"2",
"0"
] | D | easy | decoy |
C#CCCCCO[SiH](C)C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCCO[SiH](C)C: nitrile, silane, and thiocyanate? | [
"0",
"1",
"2",
"3"
] | A | easy | decoy |
C#CCCCCn1c(-c2cccnc2)nnc1N1CCC2(CCN(C)C2=O)CC1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCCn1c(-c2cccnc2)nnc1N1CCC2(CCN(C)C2=O)CC1: carbazone, thioarene, and thioketone? | [
"3",
"0",
"2",
"1"
] | B | easy | decoy |
C#CCCCN1CCC[C@H]1COc1nc2c(c(N3CCN(C(=O)C(Cl)Cl)[C@@H](CC#N)C3)n1)CCN(c1cccc3ccc(F)c(Cl)c13)C2 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCN1CCC[C@H]1COc1nc2c(c(N3CCN(C(=O)C(Cl)Cl)[C@@H](CC#N)C3)n1)CCN(c1cccc3ccc(F)c(Cl)c13)C2: aryl bromide, carbodiimide, and secondary amine? | [
"2",
"1",
"0",
"3"
] | C | easy | decoy |
C#CCCCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O: hemiacetal, sulfenic acid, and sulfenic derivative? | [
"2",
"1",
"0",
"3"
] | C | easy | decoy |
C#CCCCc1cc2cn(C/C=C3\OC(=O)C(OCc4ccccc4)=C3OCc3ccccc3)c(=O)nc2o1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCCc1cc2cn(C/C=C3\OC(=O)C(OCc4ccccc4)=C3OCc3ccccc3)c(=O)nc2o1: carbonic acid monoester, carboxylic anhydride, and thiocyanate? | [
"3",
"1",
"0",
"2"
] | C | easy | decoy |
C#CCCN(C)CCN(C)c1ccc(Nc2ncc(Cl)c(O[C@@H]3CO[C@H]4[C@@H]3OC[C@H]4OC)n2)cc1NC(=O)C=C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCN(C)CCN(C)c1ccc(Nc2ncc(Cl)c(O[C@@H]3CO[C@H]4[C@@H]3OC[C@H]4OC)n2)cc1NC(=O)C=C: acylhydrazone, hydroxamic acid ester, and sulfinic ester? | [
"1",
"3",
"2",
"0"
] | D | easy | decoy |
C#CCCN(CC(C)C)C[C@@]1(C)CC1(F)F | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCN(CC(C)C)C[C@@]1(C)CC1(F)F: aryl bromide, aryl iodide, and sulfilimine? | [
"0",
"1",
"2",
"3"
] | A | easy | decoy |
C#CCCN1CC[C@H](N2CCN(C(=O)C[C@@H]3CCNC3=O)CC2)C1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCN1CC[C@H](N2CCN(C(=O)C[C@@H]3CCNC3=O)CC2)C1: hydrazine, hydroxamic acid ester, and primary amine? | [
"1",
"3",
"2",
"0"
] | D | easy | decoy |
C#CCCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccccc4)cc32)c1C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCNC(=O)c1c(C)[nH]c(/C=C2\C(=O)Nc3ccc(C(=O)N[C@H](C)c4ccccc4)cc32)c1C: dicarbodiazene, hydroxylamine, and isocyanate? | [
"0",
"1",
"2",
"3"
] | A | easy | decoy |
C#CCCOc1ccc(C(=O)c2ccc(CCC(=O)N3CCC(CCNCc4cc(-c5cc(-c6cccc(C(F)(F)F)c6)ccc5Oc5ccc(S(=O)(=O)Nc6ncns6)cc5C#N)ccn4)CC3)cc2)cc1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCOc1ccc(C(=O)c2ccc(CCC(=O)N3CCC(CCNCc4cc(-c5cc(-c6cccc(C(F)(F)F)c6)ccc5Oc5ccc(S(=O)(=O)Nc6ncns6)cc5C#N)ccn4)CC3)cc2)cc1: aminal, hydrazine, and thiocyanate? | [
"3",
"2",
"1",
"0"
] | D | easy | decoy |
C#CCCOc1cccc(N/C(C)=C2\C(=O)NN(Cc3ccccc3)C2=O)c1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCOc1cccc(N/C(C)=C2\C(=O)NN(Cc3ccccc3)C2=O)c1: isothiourea, primary amine, and semicarbazide? | [
"0",
"3",
"1",
"2"
] | A | easy | decoy |
C#CCCn1cc(-c2cccc3c2ccn3C(=O)C2CCCN2C#N)c(C(F)(F)F)n1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCCn1cc(-c2cccc3c2ccn3C(=O)C2CCCN2C#N)c(C(F)(F)F)n1: carbonic acid esterhalide, hydrazone, and thioketone? | [
"1",
"2",
"0",
"3"
] | C | easy | decoy |
C#CCN(C(=O)CCC(F)(F)C(F)(F)F)c1cn(-c2cccnc2)nc1Cl | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C(=O)CCC(F)(F)C(F)(F)F)c1cn(-c2cccnc2)nc1Cl: carbazide, primary amine, and semicarbazide? | [
"2",
"1",
"0",
"3"
] | C | easy | decoy |
C#CCN(C(=O)NC[C@@H]1CSc2ccccc21)[C@@H]1CCCc2ccccc21 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C(=O)NC[C@@H]1CSc2ccccc21)[C@@H]1CCCc2ccccc21: hydroxamic acid ester, semicarbazide, and thioaldehyde? | [
"3",
"1",
"0",
"2"
] | C | easy | decoy |
C#CCN(C)C(=C)c1ccc[nH]1 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C)C(=C)c1ccc[nH]1: carbodiimide, primary amine, and thioaldehyde? | [
"1",
"0",
"3",
"2"
] | B | easy | decoy |
C#CCN(C)C(=O)N1[C@@H](C)CNC[C@@H]1C | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C)C(=O)N1[C@@H](C)CNC[C@@H]1C: acylhydrazone, carbodiimide, and hydrazine? | [
"1",
"0",
"3",
"2"
] | B | easy | decoy |
C#CCN(C)C(=O)OC[C@@H]1CC[C@]2(COc3nc(N4C[C@H]5CC[C@@H](C4)N5)c4cnc(-c5cc(O)cc6ccc(F)c(C#C)c56)c(F)c4n3)CCCN12 | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C)C(=O)OC[C@@H]1CC[C@]2(COc3nc(N4C[C@H]5CC[C@@H](C4)N5)c4cnc(-c5cc(O)cc6ccc(F)c(C#C)c56)c(F)c4n3)CCCN12: enolether, hemiketal, and primary amine? | [
"1",
"0",
"3",
"2"
] | B | easy | decoy |
C#CCN(C)C(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2)CCCC(=O)N3C)ncc1Cl | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C)C(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2)CCCC(=O)N3C)ncc1Cl: acylhydrazone, semicarbazide, and thioaldehyde? | [
"1",
"2",
"0",
"3"
] | C | easy | decoy |
C#CCN(C)C(C)CCCCO | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C)C(C)CCCCO: guanidine, hydroperoxide, and thioaldehyde? | [
"0",
"1",
"3",
"2"
] | A | easy | decoy |
C#CCN(C)CC[C@H](CSc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(-c3ccc(F)cc3)c(S(=O)(=O)F)c2)cc1S(=O)(=O)C(F)(F)F | count_present | How many of the following functional groups are present in the molecule with SMILES C#CCN(C)CC[C@H](CSc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(-c3ccc(F)cc3)c(S(=O)(=O)F)c2)cc1S(=O)(=O)C(F)(F)F: sulfenic derivative, sulfinic derivative, and thiocarbonic acid monoester? | [
"2",
"1",
"0",
"3"
] | C | easy | decoy |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.