accession stringlengths 6 10 | name stringlengths 8 11 | Full Name stringlengths 2 102 ⌀ | taxon stringclasses 1
value | sequence stringlengths 48 2.3k | function stringlengths 15 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q49MG5 | MAP9_HUMAN | Aster-associated protein | Homo | <M><S><D><E><V><F><S><T><T><L><A><Y><T><K><S><P><K><V><T><K><R><T><T><F><Q><D><E><L><I><R><A><I><T><A><R><S><A><R><Q><R><S><S><E><Y><S><D><D><F><D><S><D><E><I><V><S><L><G><D><F><S><D><T><S><A><D><E><N><S><V><N><K><K><M><N><D><F><H><I><S><D><D><E><E><K><N><P><S><K><L><L><F><L><K><T><N><K><S><N><G><N><I><T><K><D><E><P><V... | Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.<BOP> | Q49MG5 |
P13716 | HEM2_HUMAN | Porphobilinogen synthase | Homo | <M><Q><P><Q><S><V><L><H><S><G><Y><F><H><P><L><L><R><A><W><Q><T><A><T><T><T><L><N><A><S><N><L><I><Y><P><I><F><V><T><D><V><P><D><D><I><Q><P><I><T><S><L><P><G><V><A><R><Y><G><V><K><R><L><E><E><M><L><R><P><L><V><E><E><G><L><R><C><V><L><I><F><G><V><P><S><R><V><P><K><D><E><R><G><S><A><A><D><S><E><E><S><P><A><I><E><A><I><H><L... | Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.<BOP> | P13716 |
P52736 | ZN133_HUMAN | Zinc finger protein 150 | Homo | <M><A><F><R><D><V><A><V><D><F><T><Q><D><E><W><R><L><L><S><P><A><Q><R><T><L><Y><R><E><V><M><L><E><N><Y><S><N><L><V><S><L><G><I><S><F><S><K><P><E><L><I><T><Q><L><E><Q><G><K><E><T><W><R><E><E><K><K><C><S><P><A><T><C><P><A><D><P><E><P><E><L><Y><L><D><P><F><C><P><P><G><F><S><S><Q><K><F><P><M><Q><H><V><L><C><N><H><P><P><W><I... | May be involved in transcriptional regulation as a repressor.<BOP> | P52736 |
Q01718 | ACTHR_HUMAN | Melanocortin receptor 2 | Homo | <M><K><H><I><I><N><S><Y><E><N><I><N><N><T><A><R><N><N><S><D><C><P><R><V><V><L><P><E><E><I><F><F><T><I><S><I><V><G><V><L><E><N><L><I><V><L><L><A><V><F><K><N><K><N><L><Q><A><P><M><Y><F><F><I><C><S><L><A><I><S><D><M><L><G><S><L><Y><K><I><L><E><N><I><L><I><I><L><R><N><M><G><Y><L><K><P><R><G><S><F><E><T><T><A><D><D><I><I><D... | Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).<BOP> | Q01718 |
Q8NGG4 | OR8H1_HUMAN | Olfactory receptor OR11-180 | Homo | <M><G><R><R><N><N><T><N><V><P><D><F><I><L><T><G><L><S><D><S><E><E><V><Q><M><A><L><F><I><L><F><L><L><I><Y><L><I><T><M><L><G><N><V><G><M><I><L><I><I><R><L><D><L><Q><L><H><T><P><M><Y><F><F><L><T><H><L><S><F><I><D><L><S><Y><S><T><V><I><T><P><K><T><L><A><N><L><L><T><S><N><Y><I><S><F><M><G><C><F><A><Q><M><F><F><F><V><F><L><G... | Odorant receptor.<BOP> | Q8NGG4 |
P53816 | PLAT3_HUMAN | Renal carcinoma antigen NY-REN-65 | Homo | <M><R><A><P><I><P><E><P><K><P><G><D><L><I><E><I><F><R><P><F><Y><R><H><W><A><I><Y><V><G><D><G><Y><V><V><H><L><A><P><P><S><E><V><A><G><A><G><A><A><S><V><M><S><A><L><T><D><K><A><I><V><K><K><E><L><L><Y><D><V><A><G><S><D><K><Y><Q><V><N><N><K><H><D><D><K><Y><S><P><L><P><C><S><K><I><I><Q><R><A><E><E><L><V><G><Q><E><V><L><Y><K... | (Microbial infection) Acts as a host factor for picornaviruses: required during early infection to promote viral genome release into the cytoplasm . May act as a cellular sensor of membrane damage at sites of virus entry, which relocalizes to sites of membrane rupture upon virus unfection . Facilitates safe passage of ... | P53816 |
Q9H4B0 | OSGL1_HUMAN | tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1 | Homo | <M><L><I><L><T><K><T><A><G><V><F><F><K><P><S><K><R><K><V><Y><E><F><L><R><S><F><N><F><H><P><G><T><L><F><L><H><K><I><V><L><G><I><E><T><S><C><D><D><T><A><A><A><V><V><D><E><T><G><N><V><L><G><E><A><I><H><S><Q><T><E><V><H><L><K><T><G><G><I><V><P><P><A><A><Q><Q><L><H><R><E><N><I><Q><R><I><V><Q><E><A><L><S><A><S><G><V><S><P><S... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maint... | Q9H4B0 |
Q9BSJ6 | PIMRE_HUMAN | Regulator of chromosome segregation protein 1 | Homo | <M><A><S><R><W><Q><N><M><G><T><S><V><R><R><R><S><L><Q><H><Q><E><Q><L><E><D><S><K><E><L><Q><P><V><V><S><H><Q><E><T><S><V><G><A><L><G><S><L><C><R><Q><F><Q><R><R><L><P><L><R><A><V><N><L><N><L><R><A><G><P><S><W><K><R><L><E><T><P><E><P><G><Q><Q><G><L><Q><A><A><A><R><S><A><K><S><A><L><G><A><V><S><Q><R><I><Q><E><S><C><Q><S><G... | During mitosis, may play a role in the control of metaphase-to-anaphase transition.<BOP> | Q9BSJ6 |
P49770 | EI2BB_HUMAN | eIF-2B GDP-GTP exchange factor subunit beta | Homo | <M><P><G><S><A><A><K><G><S><E><L><S><E><R><I><E><S><F><V><E><T><L><K><R><G><G><G><P><R><S><S><E><E><M><A><R><E><T><L><G><L><L><R><Q><I><I><T><D><H><R><W><S><N><A><G><E><L><M><E><L><I><R><R><E><G><R><R><M><T><A><A><Q><P><S><E><T><T><V><G><N><M><V><R><R><V><L><K><I><I><R><E><E><Y><G><R><L><H><G><R><S><D><E><S><D><Q><Q><E... | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.<BOP> | P49770 |
Q9H3J6 | MTRFR_HUMAN | Mitochondrial translation release factor in rescue | Homo | <M><S><T><V><G><L><F><H><F><P><T><P><L><T><R><I><C><P><A><P><W><G><L><R><L><W><E><K><L><T><L><L><S><P><G><I><A><V><T><P><V><Q><M><A><G><K><K><D><Y><P><A><L><L><S><L><D><E><N><E><L><E><E><Q><F><V><K><G><H><G><P><G><G><Q><A><T><N><K><T><S><N><C><V><V><L><K><H><I><P><S><G><I><V><V><K><C><H><Q><T><R><S><V><D><Q><N><R><K><L... | Part of a mitoribosome-associated quality control pathway that prevents aberrant translation by responding to interruptions during elongation . As heterodimer with MTRES1, ejects the unfinished nascent chain and peptidyl transfer RNA (tRNA), respectively, from stalled ribosomes. Recruitment of mitoribosome biogenesis f... | Q9H3J6 |
P19237 | TNNI1_HUMAN | Troponin I, slow-twitch isoform | Homo | <M><P><E><V><E><R><K><P><K><I><T><A><S><R><K><L><L><L><K><S><L><M><L><A><K><A><K><E><C><W><E><Q><E><H><E><E><R><E><A><E><K><V><R><Y><L><A><E><R><I><P><T><L><Q><T><R><G><L><S><L><S><A><L><Q><D><L><C><R><E><L><H><A><K><V><E><V><V><D><E><E><R><Y><D><I><E><A><K><C><L><H><N><T><R><E><I><K><D><L><K><L><K><V><M><D><L><R><G><K... | Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.<BOP> | P19237 |
Q96H86 | ZN764_HUMAN | Zinc finger protein 764 | Homo | <M><A><P><P><L><A><P><L><P><P><R><D><P><N><G><A><G><P><E><W><R><E><P><G><A><V><S><F><A><D><V><A><V><Y><F><C><R><E><E><W><G><C><L><R><P><A><Q><R><A><L><Y><R><D><V><M><R><E><T><Y><G><H><L><S><A><L><G><I><G><G><N><K><P><A><L><I><S><W><V><E><E><E><A><E><L><W><G><P><A><A><Q><D><P><E><V><A><K><C><Q><T><Q><T><D><P><A><D><S><R... | May be involved in transcriptional regulation.<BOP> | Q96H86 |
Q8NH74 | O10A6_HUMAN | Olfactory receptor OR11-96 | Homo | <M><E><R><Q><N><Q><S><C><V><V><E><F><I><L><L><G><F><S><N><Y><P><E><L><Q><G><Q><L><F><V><A><F><L><V><I><Y><L><V><T><L><I><G><N><A><I><I><I><V><I><V><S><L><D><Q><S><L><H><V><P><M><Y><L><F><L><L><N><L><S><V><V><D><L><S><F><S><A><V><I><M><P><E><M><L><V><V><L><S><T><E><K><T><T><I><S><F><G><G><C><F><A><Q><M><Y><F><I><L><L><F... | Odorant receptor.<BOP> | Q8NH74 |
Q96I51 | RCC1L_HUMAN | Williams-Beuren syndrome chromosomal region 16 protein | Homo | <M><A><L><V><A><L><V><A><G><A><R><L><G><R><R><L><S><G><P><G><L><G><R><G><H><W><T><A><A><G><R><S><R><S><R><R><E><A><A><E><A><E><A><E><V><P><V><V><Q><Y><V><G><E><R><A><A><R><A><D><R><V><F><V><W><G><F><S><F><S><G><A><L><G><V><P><S><F><V><V><P><S><S><G><P><G><P><R><A><G><A><R><P><R><R><R><I><Q><P><V><P><Y><R><L><E><L><D><Q... | Guanine nucleotide exchange factor (GEF) for mitochondrial dynamin-related GTPase OPA1. Activates OPA1, by exchanging bound GDP for free GTP, and drives OPA1 and MFN1-dependent mitochondrial fusion . Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consist... | Q96I51 |
P17152 | TMM11_HUMAN | Protein PMI | Homo | <M><A><A><W><G><R><R><R><L><G><P><G><S><S><G><G><S><A><R><E><R><V><S><L><S><A><T><D><C><Y><I><V><H><E><I><Y><N><G><E><N><A><Q><D><Q><F><E><Y><E><L><E><Q><A><L><E><A><Q><Y><K><Y><I><V><I><E><P><T><R><I><G><D><E><T><A><R><W><I><T><V><G><N><C><L><H><K><T><A><V><L><A><G><T><A><C><L><F><T><P><L><A><L><P><L><D><Y><S><H><Y><I... | Plays a role in mitochondrial morphogenesis.<BOP> | P17152 |
P35318 | ADML_HUMAN | ProAM N-terminal 20 peptide | Homo | <M><K><L><V><S><V><A><L><M><Y><L><G><S><L><A><F><L><G><A><D><T><A><R><L><D><V><A><S><E><F><R><K><K><W><N><K><W><A><L><S><R><G><K><R><E><L><R><M><S><S><S><Y><P><T><G><L><A><D><V><K><A><G><P><A><Q><T><L><I><R><P><Q><D><M><K><G><A><S><R><S><P><E><D><S><S><P><D><A><A><R><I><R><V><K><R><Y><R><Q><S><M><N><N><F><Q><G><L><R><S... | AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, ... | P35318 |
Q7L2K0 | TEDC2_HUMAN | Tubulin epsilon and delta complex protein 2 | Homo | <M><L><P><A><G><C><S><R><R><L><V><A><E><L><Q><G><A><L><D><A><C><A><Q><R><Q><L><Q><L><E><Q><S><L><R><V><C><R><R><L><L><H><A><W><E><P><T><G><T><R><A><L><K><P><P><P><G><P><E><T><N><G><E><D><P><L><P><A><C><T><P><S><P><Q><D><L><K><E><L><E><F><L><T><Q><A><L><E><K><A><V><R><V><R><R><G><I><T><K><A><G><E><R><D><K><A><P><S><L><K... | Acts as a positive regulator of ciliary hedgehog signaling. Required for centriole stability.<BOP> | Q7L2K0 |
P05013 | IFNA6_HUMAN | Interferon alpha-K | Homo | <M><A><L><P><F><A><L><L><M><A><L><V><V><L><S><C><K><S><S><C><S><L><D><C><D><L><P><Q><T><H><S><L><G><H><R><R><T><M><M><L><L><A><Q><M><R><R><I><S><L><F><S><C><L><K><D><R><H><D><F><R><F><P><Q><E><E><F><D><G><N><Q><F><Q><K><A><E><A><I><S><V><L><H><E><V><I><Q><Q><T><F><N><L><F><S><T><K><D><S><S><V><A><W><D><E><R><L><L><D><K... | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.<BOP> | P05013 |
P47985 | UCRI_HUMAN | Ubiquinol-cytochrome c reductase 8 kDa protein | Homo | <M><L><S><V><A><S><R><S><G><P><F><A><P><V><L><S><A><T><S><R><G><V><A><G><A><L><R><P><L><V><Q><A><T><V><P><A><T><P><E><Q><P><V><L><D><L><K><R><P><F><L><S><R><E><S><L><S><G><Q><A><V><R><R><P><L><V><A><S><V><G><L><N><V><P><A><S><V><C><Y><S><H><T><D><I><K><V><P><D><F><S><E><Y><R><R><L><E><V><L><D><S><T><K><S><S><R><E><S><S... | Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII). UQCRFS1 undergoes proteolytic processing once it is incorporated in the complex III dimer. One of the fragments, called subunit 9, corresponds to its mitochondrial targeting sequence (MTS). The proteolytic processing is... | P47985 |
P45985 | MP2K4_HUMAN | c-Jun N-terminal kinase kinase 1 | Homo | <M><A><A><P><S><P><S><G><G><G><G><S><G><G><G><S><G><S><G><T><P><G><P><V><G><S><P><A><P><G><H><P><A><V><S><S><M><Q><G><K><R><K><A><L><K><L><N><F><A><N><P><P><F><K><S><T><A><R><F><T><L><N><P><N><P><T><G><V><Q><N><P><H><I><E><R><L><R><T><H><S><I><E><S><S><G><K><L><K><I><S><P><E><Q><H><W><D><F><T><A><E><D><L><K><D><L><G><E... | Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly activate the stress-activa... | P45985 |
Q96NT5 | PCFT_HUMAN | Solute carrier family 46 member 1 | Homo | <M><E><G><S><A><S><P><P><E><K><P><R><A><R><P><A><A><A><V><L><C><R><G><P><V><E><P><L><V><F><L><A><N><F><A><L><V><L><Q><G><P><L><T><T><Q><Y><L><W><H><R><F><S><A><D><L><G><Y><N><G><T><R><Q><R><G><G><C><S><N><R><S><A><D><P><T><M><Q><E><V><E><T><L><T><S><H><W><T><L><Y><M><N><V><G><G><F><L><V><G><L><F><S><S><T><L><L><G><A><W... | Inactive isoform which is not able to mediate proton-coupled folate transport.<BOP> | Q96NT5 |
Q9HBY8 | SGK2_HUMAN | Serum/glucocorticoid-regulated kinase 2 | Homo | <M><N><S><S><P><A><G><T><P><S><P><Q><P><S><R><A><N><G><N><I><N><L><G><P><S><A><N><P><N><A><Q><P><T><D><F><D><F><L><K><V><I><G><K><G><N><Y><G><K><V><L><L><A><K><R><K><S><D><G><A><F><Y><A><V><K><V><L><Q><K><K><S><I><L><K><K><K><E><Q><S><H><I><M><A><E><R><S><V><L><L><K><N><V><R><H><P><F><L><V><G><L><R><Y><S><F><Q><T><P><E... | Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up-regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAA... | Q9HBY8 |
Q8IUC8 | GLT13_HUMAN | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13 | Homo | <M><R><R><F><V><Y><C><K><V><V><L><A><T><S><L><M><W><V><L><V><D><V><F><L><L><L><Y><F><S><E><C><N><K><C><D><D><K><K><E><R><S><L><L><P><A><L><R><A><V><I><S><R><N><Q><E><G><P><G><E><M><G><K><A><V><L><I><P><K><D><D><Q><E><K><M><K><E><L><F><K><I><N><Q><F><N><L><M><A><S><D><L><I><A><L><N><R><S><L><P><D><V><R><L><E><G><C><K><T... | Can glycosylate both unmodified peptides and glycopeptides that already contain an O-linked GalNAc sugar. Transfers GalNAc to Thr-/Ser-rich tandem repeats GTTPSPVPTTSTTSAP of MUC5AC, specifically on Thr-3 of non-glycosylated MUC5AC peptide, on Thr-12 and Thr-13 of preglycosylated MUC5AC at Thr-3 (MUC5AC-3), on Thr-3 of... | Q8IUC8 |
Q14558 | KPRA_HUMAN | 39 kDa phosphoribosypyrophosphate synthase-associated protein | Homo | <M><N><A><A><R><T><G><Y><R><V><F><S><A><N><S><T><A><A><C><T><E><L><A><K><R><I><T><E><R><L><G><A><E><L><G><K><S><V><V><Y><Q><E><T><N><G><E><T><R><V><E><I><K><E><S><V><R><G><Q><D><I><F><I><I><Q><T><I><P><R><D><V><N><T><A><V><M><E><L><L><I><M><A><Y><A><L><K><T><A><C><A><R><N><I><I><G><V><I><P><Y><F><P><Y><S><K><Q><S><K><M... | Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.<BOP> | Q14558 |
O94992 | HEXI1_HUMAN | Menage a quatre protein 1 | Homo | <M><A><E><P><F><L><S><E><Y><Q><H><Q><P><Q><T><S><N><C><T><G><A><A><A><V><Q><E><E><L><N><P><E><R><P><P><G><A><E><E><R><V><P><E><E><D><S><R><W><Q><S><R><A><F><P><Q><L><G><G><R><P><G><P><E><G><E><G><S><L><E><S><Q><P><P><P><L><Q><T><Q><A><C><P><E><S><S><C><L><R><E><G><E><K><G><Q><N><G><D><D><S><S><A><G><G><D><F><P><P><P><A... | Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor . Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation . May als... | O94992 |
Q53EZ4 | CEP55_HUMAN | Up-regulated in colon cancer 6 | Homo | <M><S><S><R><S><T><K><D><L><I><K><S><K><W><G><S><K><P><S><N><S><K><S><E><T><T><L><E><K><L><K><G><E><I><A><H><L><K><T><S><V><D><E><I><T><S><G><K><G><K><L><T><D><K><E><R><H><R><L><L><E><K><I><R><V><L><E><A><E><K><E><K><N><A><Y><Q><L><T><E><K><D><K><E><I><Q><R><L><R><D><Q><L><K><A><R><Y><S><T><T><T><L><L><E><Q><L><E><E><T... | Plays a role in mitotic exit and cytokinesis . Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis . Not required for microtubule nucleation . Plays a role in the development of the brain and kidney .<BOP> | Q53EZ4 |
Q9NS85 | CAH10_HUMAN | Cerebral protein 15 | Homo | <M><E><I><V><W><E><V><L><F><L><L><Q><A><N><F><I><V><C><I><S><A><Q><Q><N><S><P><K><I><H><E><G><W><W><A><Y><K><E><V><V><Q><G><S><F><V><P><V><P><S><F><W><G><L><V><N><S><A><W><N><L><C><S><V><G><K><R><Q><S><P><V><N><I><E><T><S><H><M><I><F><D><P><F><L><T><P><L><R><I><N><T><G><G><R><K><V><S><G><T><M><Y><N><T><G><R><H><V><S><L... | Does not have a catalytic activity.<BOP> | Q9NS85 |
Q8TCB7 | METL6_HUMAN | Methyltransferase-like protein 6 | Homo | <M><A><S><L><Q><R><K><G><L><Q><A><R><I><L><T><S><E><E><E><E><K><L><K><R><D><Q><T><L><V><S><D><F><K><Q><Q><K><L><E><Q><E><A><Q><K><N><W><D><L><F><Y><K><R><N><S><T><N><F><F><K><D><R><H><W><T><T><R><E><F><E><E><L><R><S><C><R><E><F><E><D><Q><K><L><T><M><L><E><A><G><C><G><V><G><N><C><L><F><P><L><L><E><E><D><P><N><I><F><A><Y... | S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Ser), including tRNA(Ser)(UGA) and tRNA(Ser)(GCU) . Interaction with SARS1/SerRS is required for N(3)-methylcytidine methylation .<BOP> | Q8TCB7 |
P30154 | 2AAB_HUMAN | PP2A subunit A isoform R1-beta | Homo | <M><A><G><A><S><E><L><G><T><G><P><G><A><A><G><G><D><G><D><D><S><L><Y><P><I><A><V><L><I><D><E><L><R><N><E><D><V><Q><L><R><L><N><S><I><K><K><L><S><T><I><A><L><A><L><G><V><E><R><T><R><S><E><L><L><P><F><L><T><D><T><I><Y><D><E><D><E><V><L><L><A><L><A><E><Q><L><G><N><F><T><G><L><V><G><G><P><D><F><A><H><C><L><L><P><P><L><E><N... | The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.<BOP> | P30154 |
Q9Y227 | ENTP4_HUMAN | Uridine-diphosphatase | Homo | <M><G><R><I><G><I><S><C><L><F><P><A><S><W><H><F><S><I><S><P><V><G><C><P><R><I><L><N><T><N><L><R><Q><I><M><V><I><S><V><L><A><A><A><V><S><L><L><Y><F><S><V><V><I><I><R><N><K><Y><G><R><L><T><R><D><K><K><F><Q><R><Y><L><A><R><V><T><D><I><E><A><T><D><T><N><N><P><N><V><N><Y><G><I><V><V><D><C><G><S><S><G><S><R><V><F><V><Y><C><W... | Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP). Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP. Can use either Ca(2+) or Mg(2+) equally.<BOP> | Q9Y227 |
Q9GZP1 | NRSN2_HUMAN | Neurensin-2 | Homo | <M><M><P><S><C><N><R><S><C><S><C><S><R><G><P><S><V><E><D><G><K><W><Y><G><V><R><S><Y><L><H><L><F><Y><E><D><C><A><G><T><A><L><S><D><D><P><E><G><P><P><V><L><C><P><R><R><P><W><P><S><L><C><W><K><I><S><L><S><S><G><T><L><L><L><L><L><G><V><A><A><L><T><T><G><Y><A><V><P><P><K><L><E><G><I><G><E><G><E><F><L><V><L><D><Q><R><A><A><D... | May play a role in maintenance and/or transport of vesicles.<BOP> | Q9GZP1 |
P20853 | CP2A7_HUMAN | Cytochrome P450 IIA4 | Homo | <M><L><A><S><G><L><L><L><V><A><L><L><A><C><L><T><V><M><V><L><M><S><V><W><Q><Q><R><K><S><R><G><K><L><P><P><G><P><T><P><L><P><F><I><G><N><Y><L><Q><L><N><T><E><H><I><C><D><S><I><M><K><F><S><E><C><Y><G><P><V><F><T><I><H><L><G><P><R><R><V><V><V><L><C><G><H><D><A><V><R><E><A><L><V><D><Q><A><E><E><F><S><G><R><G><E><Q><A><T><F... | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.<BOP> | P20853 |
P0C7N5 | OR8U9_HUMAN | Olfactory receptor 8U9 | Homo | <M><T><Q><I><N><C><T><Q><V><T><E><F><I><L><V><G><L><T><D><R><Q><E><L><K><M><P><L><F><V><L><F><L><S><I><Y><L><F><T><V><V><G><N><L><G><L><I><L><L><I><R><T><D><E><K><L><N><T><P><M><Y><F><F><L><S><N><L><A><F><V><D><F><C><Y><S><S><V><I><T><P><K><M><L><G><N><F><L><Y><K><Q><N><S><I><S><F><N><A><C><A><A><Q><L><G><C><F><L><A><F... | Odorant receptor.<BOP> | P0C7N5 |
O75509 | TNR21_HUMAN | Death receptor 6 | Homo | <M><G><T><S><P><S><S><S><T><A><L><A><S><C><S><R><I><A><R><R><A><T><A><T><M><I><A><G><S><L><L><L><L><G><F><L><S><T><T><T><A><Q><P><E><Q><K><A><S><N><L><I><G><T><Y><R><H><V><D><R><A><T><G><Q><V><L><T><C><D><K><C><P><A><G><T><Y><V><S><E><H><C><T><N><T><S><L><R><V><C><S><S><C><P><V><G><T><F><T><R><H><E><N><G><I><E><K><C><H... | Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Plays a role in neuronal apoptosis, including apoptosis in response to amyloid peptides derived from APP, and is ... | O75509 |
P17707 | DCAM_HUMAN | S-adenosylmethionine decarboxylase beta chain | Homo | <M><E><A><A><H><F><F><E><G><T><E><K><L><L><E><V><W><F><S><R><Q><Q><P><D><A><N><Q><G><S><G><D><L><R><T><I><P><R><S><E><W><D><I><L><L><K><D><V><Q><C><S><I><I><S><V><T><K><T><D><K><Q><E><A><Y><V><L><S><E><S><S><M><F><V><S><K><R><R><F><I><L><K><T><C><G><T><T><L><L><L><K><A><L><V><P><L><L><K><L><A><R><D><Y><S><G><F><D><S><I... | Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.<BOP> | P17707 |
Q9HB20 | PKHA3_HUMAN | Phosphatidylinositol-four-phosphate adapter protein 1 | Homo | <M><E><G><V><L><Y><K><W><T><N><Y><L><T><G><W><Q><P><R><W><F><V><L><D><N><G><I><L><S><Y><Y><D><S><Q><D><D><V><C><K><G><S><K><G><S><I><K><M><A><V><C><E><I><K><V><H><S><A><D><N><T><R><M><E><L><I><I><P><G><E><Q><H><F><Y><M><K><A><V><N><A><A><E><R><Q><R><W><L><V><A><L><G><S><S><K><A><C><L><T><D><T><R><T><K><K><E><K><E><I><S... | Plays a role in regulation of vesicular cargo transport from the trans-Golgi network (TGN) to the plasma membrane . Regulates Golgi phosphatidylinositol 4-phosphate (PtdIns(4)P) levels and activates the PtdIns(4)P phosphatase activity of SACM1L when it binds PtdIns(4)P in 'trans' configuration . Binds preferentially to... | Q9HB20 |
O60238 | BNI3L_HUMAN | NIP3-like protein X | Homo | <M><S><S><H><L><V><E><P><P><P><P><L><H><N><N><N><N><N><C><E><E><N><E><Q><S><L><P><P><P><A><G><L><N><S><S><W><V><E><L><P><M><N><S><S><N><G><N><D><N><G><N><G><K><N><G><G><L><E><H><V><P><S><S><S><S><I><H><N><G><D><M><E><K><I><L><L><D><A><Q><H><E><S><G><Q><S><S><S><R><G><S><S><H><C><D><S><P><S><P><Q><E><D><G><Q><I><M><F><D... | Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in respons... | O60238 |
Q6P280 | ZN529_HUMAN | Zinc finger protein 529 | Homo | <M><A><N><S><S><F><I><G><D><H><V><H><G><A><P><H><A><V><M><P><E><V><E><F><P><D><Q><F><F><T><V><L><T><M><D><H><E><L><V><T><L><R><D><V><V><I><N><F><S><Q><E><E><W><E><Y><L><D><S><A><Q><R><N><L><Y><W><D><V><M><M><E><N><Y><S><N><L><L><S><L><D><L><E><S><R><N><E><T><K><H><L><S><V><G><K><D><I><I><Q><N><T><G><S><Q><W><E><V><M><E... | May be involved in transcriptional regulation.<BOP> | Q6P280 |
P48651 | PTSS1_HUMAN | Serine-exchange enzyme I | Homo | <M><A><S><C><V><G><S><R><T><L><S><K><D><D><V><N><Y><K><M><H><F><R><M><I><N><E><Q><Q><V><E><D><I><T><I><D><F><F><Y><R><P><H><T><I><T><L><L><S><F><T><I><V><S><L><M><Y><F><A><F><T><R><D><D><S><V><P><E><D><N><I><W><R><G><I><L><S><V><I><F><F><F><L><I><I><S><V><L><A><F><P><N><G><P><F><T><R><P><H><P><A><L><W><R><M><V><F><G><L... | Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine . Catalyzes mainly the conversion of phosphatidylcholine . Also converts, in vitro and to a lesser extent, phosphatidylethanolamine .<BOP> | P48651 |
Q6N075 | MFSD5_HUMAN | Molybdate transporter 2 homolog | Homo | <M><L><V><T><A><Y><L><A><F><V><G><L><L><A><S><C><L><G><L><E><L><S><R><C><R><A><K><P><P><G><R><A><C><S><N><P><S><F><L><R><F><Q><L><D><F><Y><Q><V><Y><F><L><A><L><A><A><D><W><L><Q><A><P><Y><L><Y><K><L><Y><Q><H><Y><Y><F><L><E><G><Q><I><A><I><L><Y><V><C><G><L><A><S><T><V><L><F><G><L><V><A><S><S><L><V><D><W><L><G><R><K><N><S... | Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.<BOP> | Q6N075 |
Q969S2 | NEIL2_HUMAN | Nei-like protein 2 | Homo | <M><P><E><G><P><L><V><R><K><F><H><H><L><V><S><P><F><V><G><Q><Q><V><V><K><T><G><G><S><S><K><K><L><Q><P><A><S><L><Q><S><L><W><L><Q><D><T><Q><V><H><G><K><K><L><F><L><R><F><D><L><D><E><E><M><G><P><P><G><S><S><P><T><P><E><P><P><Q><K><E><V><Q><K><E><G><A><A><D><P><K><Q><V><G><E><P><S><G><Q><K><T><L><D><G><S><S><R><S><A><E><L... | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydrox... | Q969S2 |
Q5T1S8 | NCMAP_HUMAN | Myelin protein of 11 kDa | Homo | <M><T><T><A><T><P><L><G><D><T><T><F><F><S><L><N><M><T><T><R><G><E><D><F><L><Y><K><S><S><G><A><I><V><A><A><V><V><V><V><V><I><I><I><F><T><V><V><L><I><L><L><K><M><Y><N><R><K><M><R><T><R><R><E><L><E><P><K><G><P><K><P><T><A><P><S><A><V><G><P><N><S><N><G><S><Q><H><P><A><T><V><T><F><S><P><V><D><V><Q><V><E><T><R> | Plays a role in myelin formation.<BOP> | Q5T1S8 |
O60678 | ANM3_HUMAN | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3 | Homo | <M><C><S><L><A><S><G><A><T><G><G><R><G><A><V><E><N><E><E><D><L><P><E><L><S><D><S><G><D><E><A><A><W><E><D><E><D><D><A><D><L><P><H><G><K><Q><Q><T><P><C><L><F><C><N><R><L><F><T><S><A><E><E><T><F><S><H><C><K><S><E><H><Q><F><N><I><D><S><M><V><H><K><H><G><L><E><F><Y><G><Y><I><K><L><I><N><F><I><R><L><K><N><P><T><V><E><Y><M><N... | Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases (Probable). May regulate retinoic acid synthesis and signaling by inhibiting ALDH1... | O60678 |
Q96HU8 | DIRA2_HUMAN | Distinct subgroup of the Ras family member 2 | Homo | <M><P><E><Q><S><N><D><Y><R><V><A><V><F><G><A><G><G><V><G><K><S><S><L><V><L><R><F><V><K><G><T><F><R><E><S><Y><I><P><T><V><E><D><T><Y><R><Q><V><I><S><C><D><K><S><I><C><T><L><Q><I><T><D><T><T><G><S><H><Q><F><P><A><M><Q><R><L><S><I><S><K><G><H><A><F><I><L><V><Y><S><I><T><S><R><Q><S><L><E><E><L><K><P><I><Y><E><Q><I><C><E><I... | Displays low GTPase activity and exists predominantly in the GTP-bound form.<BOP> | Q96HU8 |
Q58HT5 | AWAT1_HUMAN | Long-chain-alcohol O-fatty-acyltransferase 1 | Homo | <M><A><H><S><K><Q><P><S><H><F><Q><S><L><M><L><L><Q><W><P><L><S><Y><L><A><I><F><W><I><L><Q><P><L><F><V><Y><L><L><F><T><S><L><W><P><L><P><V><L><Y><F><A><W><L><F><L><D><W><K><T><P><E><R><G><G><R><R><S><A><W><V><R><N><W><C><V><W><T><H><I><R><D><Y><F><P><I><T><I><L><K><T><K><D><L><S><P><E><H><N><Y><L><M><G><V><H><P><H><G><L... | Acyltransferase that catalyzes the formation of ester bonds between fatty alcohols and fatty acyl-CoAs to form wax monoesters . Shows a strong preference for decyl alcohol (C10), with less activity towards C16 and C18 alcohols . Shows a strong preference for saturated acyl-CoAs .<BOP> | Q58HT5 |
P41271 | NBL1_HUMAN | Zinc finger protein DAN | Homo | <M><M><L><R><V><L><V><G><A><V><L><P><A><M><L><L><A><A><P><P><P><I><N><K><L><A><L><F><P><D><K><S><A><W><C><E><A><K><N><I><T><Q><I><V><G><H><S><G><C><E><A><K><S><I><Q><N><R><A><C><L><G><Q><C><F><S><Y><S><V><P><N><T><F><P><Q><S><T><E><S><L><V><H><C><D><S><C><M><P><A><Q><S><M><W><E><I><V><T><L><E><C><P><G><H><E><E><V><P><R... | Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.<BOP> | P41271 |
Q14CS0 | UBX2B_HUMAN | p97 cofactor p37 | Homo | <M><A><E><G><G><G><P><E><P><G><E><Q><E><R><R><S><S><G><P><R><P><P><S><A><R><D><L><Q><L><A><L><A><E><L><Y><E><D><E><V><K><C><K><S><S><K><S><N><R><P><K><A><T><V><F><K><S><P><R><T><P><P><Q><R><F><Y><S><S><E><H><E><Y><S><G><L><N><I><V><R><P><S><T><G><K><I><V><N><E><L><F><K><E><A><R><E><H><G><A><V><P><L><N><E><A><T><R><A><S... | Adapter protein required for Golgi and endoplasmic reticulum biogenesis . Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis . The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L ... | Q14CS0 |
Q9H0B6 | KLC2_HUMAN | Kinesin light chain 2 | Homo | <M><A><M><M><V><F><P><R><E><E><K><L><S><Q><D><E><I><V><L><G><T><K><A><V><I><Q><G><L><E><T><L><R><G><E><H><R><A><L><L><A><P><L><V><A><P><E><A><G><E><A><E><P><G><S><Q><E><R><C><I><L><L><R><R><S><L><E><A><I><E><L><G><L><G><E><A><Q><V><I><L><A><L><S><S><H><L><G><A><V><E><S><E><K><Q><K><L><R><A><Q><V><R><R><L><V><Q><E><N><Q... | Kinesin is a microtubule-associated force-producing protein that plays a role in organelle transport. The light chain functions in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Through binding with PLEKHM2 and ARL8B, recruits kinesin-1 to lysosomes and hence direct lysosom... | Q9H0B6 |
Q9Y315 | DEOC_HUMAN | Phosphodeoxyriboaldolase | Homo | <M><S><A><H><N><R><G><T><E><L><D><L><S><W><I><S><K><I><Q><V><N><H><P><A><V><L><R><R><A><E><Q><I><Q><A><R><R><T><V><K><K><E><W><Q><A><A><W><L><L><K><A><V><T><F><I><D><L><T><T><L><S><G><D><D><T><S><S><N><I><Q><R><L><C><Y><K><A><K><Y><P><I><R><E><D><L><L><K><A><L><N><M><H><D><K><G><I><T><T><A><A><V><C><V><Y><P><A><R><V><C... | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.<BOP> | Q9Y315 |
P51148 | RAB5C_HUMAN | RAB5L | Homo | <M><A><G><R><G><G><A><A><R><P><N><G><P><A><A><G><N><K><I><C><Q><F><K><L><V><L><L><G><E><S><A><V><G><K><S><S><L><V><L><R><F><V><K><G><Q><F><H><E><Y><Q><E><S><T><I><G><A><A><F><L><T><Q><T><V><C><L><D><D><T><T><V><K><F><E><I><W><D><T><A><G><Q><E><R><Y><H><S><L><A><P><M><Y><Y><R><G><A><Q><A><A><I><V><V><Y><D><I><T><N><T><D... | Protein transport. Probably involved in vesicular traffic.<BOP> | P51148 |
O95780 | ZN682_HUMAN | Zinc finger protein 682 | Homo | <M><E><L><L><T><F><R><D><V><T><I><E><F><S><L><E><E><W><E><F><L><N><P><A><Q><Q><S><L><Y><R><K><V><M><L><E><N><Y><R><N><L><V><S><L><G><L><T><V><S><K><P><E><L><I><S><R><L><E><Q><R><Q><E><P><W><N><V><K><R><H><E><T><I><A><K><P><P><A><M><S><S><H><Y><T><E><D><L><L><P><E><Q><C><M><Q><D><S><F><Q><K><V><I><L><R><R><Y><G><S><C><G... | May be involved in transcriptional regulation.<BOP> | O95780 |
Q9UGP5 | DPOLL_HUMAN | DNA polymerase kappa | Homo | <M><D><P><R><G><I><L><K><A><F><P><K><R><Q><K><I><H><A><D><A><S><S><K><V><L><A><K><I><P><R><R><E><E><G><E><E><A><E><E><W><L><S><S><L><R><A><H><V><V><R><T><G><I><G><R><A><R><A><E><L><F><E><K><Q><I><V><Q><H><G><G><Q><L><C><P><A><Q><G><P><G><V><T><H><I><V><V><D><E><G><M><D><Y><E><R><A><L><R><L><L><R><L><P><Q><L><P><P><G><A... | DNA polymerase that functions in several pathways of DNA repair . Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA . Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination . Has both template-depend... | Q9UGP5 |
Q9HDB9 | GAK5_HUMAN | HERV-K_3q12.3 provirus ancestral Gag polyprotein | Homo | <M><G><Q><T><K><S><K><T><K><S><K><Y><A><S><Y><L><S><F><I><K><I><L><L><K><R><G><G><V><R><V><S><T><K><N><L><I><K><L><F><Q><I><I><E><Q><F><C><P><W><F><P><E><Q><G><T><L><D><L><K><D><W><K><R><I><G><E><E><L><K><Q><A><G><R><K><G><N><I><I><P><L><T><V><W><N><D><W><A><I><I><K><A><A><L><E><P><F><Q><T><K><E><D><S><V><S><V><S><D><A... | The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding ... | Q9HDB9 |
P05162 | LEG2_HUMAN | S-Lac lectin 2 | Homo | <M><T><G><E><L><E><V><K><N><M><D><M><K><P><G><S><T><L><K><I><T><G><S><I><A><D><G><T><D><G><F><V><I><N><L><G><Q><G><T><D><K><L><N><L><H><F><N><P><R><F><S><E><S><T><I><V><C><N><S><L><D><G><S><N><W><G><Q><E><Q><R><E><D><H><L><C><F><S><P><G><S><E><V><K><F><T><V><T><F><E><S><D><K><F><K><V><K><L><P><D><G><H><E><L><T><F><P><N... | This protein binds beta-galactoside. Its physiological function is not yet known.<BOP> | P05162 |
O75496 | GEMI_HUMAN | Geminin | Homo | <M><N><P><S><M><K><Q><K><Q><E><E><I><K><E><N><I><K><N><S><S><V><P><R><R><T><L><K><M><I><Q><P><S><A><S><G><S><L><V><G><R><E><N><E><L><S><A><G><L><S><K><R><K><H><R><N><D><H><L><T><S><T><T><S><S><P><G><V><I><V><P><E><S><S><E><N><K><N><L><G><G><V><T><Q><E><S><F><D><L><M><I><K><E><N><P><S><S><Q><Y><W><K><E><V><A><E><K><R><R... | Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC) . It is degraded during the mitotic phase of the cell cycle . Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle . Inhibits histone acetyltransferase activity ... | O75496 |
Q07002 | CDK18_HUMAN | Serine/threonine-protein kinase PCTAIRE-3 | Homo | <M><I><M><N><K><M><K><N><F><K><R><R><F><S><L><S><V><P><R><T><E><T><I><E><E><S><L><A><E><F><T><E><Q><F><N><Q><L><H><N><R><R><N><E><N><L><Q><L><G><P><L><G><R><D><P><P><Q><E><C><S><T><F><S><P><T><D><S><G><E><E><P><G><Q><L><S><P><G><V><Q><F><Q><R><R><Q><N><Q><R><R><F><S><M><E><D><V><S><K><R><L><S><L><P><M><D><I><R><L><P><Q... | May play a role in signal transduction cascades in terminally differentiated cells.<BOP> | Q07002 |
P61604 | CH10_HUMAN | Early-pregnancy factor | Homo | <M><A><G><Q><A><F><R><K><F><L><P><L><F><D><R><V><L><V><E><R><S><A><A><E><T><V><T><K><G><G><I><M><L><P><E><K><S><Q><G><K><V><L><Q><A><T><V><V><A><V><G><S><G><S><K><G><K><G><G><E><I><Q><P><V><S><V><K><V><G><D><K><V><L><L><P><E><Y><G><G><T><K><V><V><L><D><D><K><D><Y><F><L><F><R><D><G><D><I><L><G><K><Y><V><D> | Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matri... | P61604 |
O43555 | GON2_HUMAN | GnRH-associated peptide II | Homo | <M><A><S><S><R><R><G><L><L><L><L><L><L><L><T><A><H><L><G><P><S><E><A><Q><H><W><S><H><G><W><Y><P><G><G><K><R><A><L><S><S><A><Q><D><P><Q><N><A><L><R><P><P><G><R><A><L><D><T><A><A><G><S><P><V><Q><T><A><H><G><L><P><S><D><A><L><A><P><L><D><D><S><M><P><W><E><G><R><T><T><A><Q><W><S><L><H><R><K><R><H><L><A><R><T><L><L><T><A><A... | Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.<BOP> | O43555 |
Q9Y5X9 | LIPE_HUMAN | Phospholipase A1 | Homo | <M><S><N><S><V><P><L><L><C><F><W><S><L><C><Y><C><F><A><A><G><S><P><V><P><F><G><P><E><G><R><L><E><D><K><L><H><K><P><K><A><T><Q><T><E><V><K><P><S><V><R><F><N><L><R><T><S><K><D><P><E><H><E><G><C><Y><L><S><V><G><H><S><Q><P><L><E><D><C><S><F><N><M><T><A><K><T><F><F><I><I><H><G><W><T><M><S><G><I><F><E><N><W><L><H><K><L><V><S... | Exerts both phospholipase and triglyceride lipase activities . More active as a phospholipase than a triglyceride lipase . Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates . Hydrolyz... | Q9Y5X9 |
Q63HQ0 | AP1AR_HUMAN | Gamma-A1-adaptin and kinesin interactor | Homo | <M><G><N><C><C><W><T><Q><C><F><G><L><L><R><K><E><A><G><R><L><Q><R><V><G><G><G><G><G><S><K><Y><F><R><T><C><S><R><G><E><H><L><T><I><E><F><E><N><L><V><E><S><D><E><G><E><S><P><G><S><S><H><R><P><L><T><E><E><E><I><V><D><L><R><E><R><H><Y><D><S><I><A><E><K><Q><K><D><L><D><K><K><I><Q><K><E><L><A><L><Q><E><E><K><L><R><L><E><E><E... | Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from ... | Q63HQ0 |
Q86UE4 | LYRIC_HUMAN | Metastasis adhesion protein | Homo | <M><A><A><R><S><W><Q><D><E><L><A><Q><Q><A><E><E><G><S><A><R><L><R><E><M><L><S><V><G><L><G><F><L><R><T><E><L><G><L><D><L><G><L><E><P><K><R><Y><P><G><W><V><I><L><V><G><T><G><A><L><G><L><L><L><L><F><L><L><G><Y><G><W><A><A><A><C><A><G><A><R><K><K><R><R><S><P><P><R><K><R><E><E><A><A><A><V><P><A><A><A><P><D><D><L><A><L><L><K... | Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an ef... | Q86UE4 |
Q7Z624 | CMKMT_HUMAN | Calmodulin-lysine N-methyltransferase | Homo | <M><E><S><R><V><A><D><A><G><T><G><E><T><A><R><A><A><G><G><S><P><A><V><G><C><T><T><R><G><P><V><V><S><A><P><L><G><A><A><R><W><K><L><L><R><Q><V><L><K><Q><K><H><L><D><D><C><L><R><H><V><S><V><R><R><F><E><S><F><N><L><F><S><V><T><E><G><K><E><R><E><T><E><E><E><V><G><A><W><V><Q><Y><T><S><I><F><C><P><E><Y><S><I><S><L><R><H><N><S... | Catalyzes the trimethylation of 'Lys-116' in calmodulin.<BOP> | Q7Z624 |
P01111 | RASN_HUMAN | Transforming protein N-Ras | Homo | <M><T><E><Y><K><L><V><V><V><G><A><G><G><V><G><K><S><A><L><T><I><Q><L><I><Q><N><H><F><V><D><E><Y><D><P><T><I><E><D><S><Y><R><K><Q><V><V><I><D><G><E><T><C><L><L><D><I><L><D><T><A><G><Q><E><E><Y><S><A><M><R><D><Q><Y><M><R><T><G><E><G><F><L><C><V><F><A><I><N><N><S><K><S><F><A><D><I><N><L><Y><R><E><Q><I><K><R><V><K><D><S><D... | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.<BOP> | P01111 |
P07951 | TPM2_HUMAN | Tropomyosin-2 | Homo | <M><D><A><I><K><K><K><M><Q><M><L><K><L><D><K><E><N><A><I><D><R><A><E><Q><A><E><A><D><K><K><Q><A><E><D><R><C><K><Q><L><E><E><E><Q><Q><A><L><Q><K><K><L><K><G><T><E><D><E><V><E><K><Y><S><E><S><V><K><E><A><Q><E><K><L><E><Q><A><E><K><K><A><T><D><A><E><A><D><V><A><S><L><N><R><R><I><Q><L><V><E><E><E><L><D><R><A><Q><E><R><L><A... | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing c... | P07951 |
Q2M218 | ZN630_HUMAN | Zinc finger protein 630 | Homo | <M><I><E><S><Q><E><P><V><T><F><E><D><V><A><V><D><F><T><Q><E><E><W><Q><Q><L><N><P><A><Q><K><T><L><H><R><D><V><M><L><E><T><Y><N><H><L><V><S><V><G><C><S><G><I><K><P><D><V><I><F><K><L><E><H><G><K><D><P><W><I><I><E><S><E><L><S><R><W><I><Y><P><D><R><V><K><G><L><E><S><S><Q><Q><I><I><S><G><E><L><L><F><Q><R><E><I><L><E><R><A><P... | May be involved in transcriptional regulation.<BOP> | Q2M218 |
Q07817 | B2CL1_HUMAN | Apoptosis regulator Bcl-X | Homo | <M><S><Q><S><N><R><E><L><V><V><D><F><L><S><Y><K><L><S><Q><K><G><Y><S><W><S><Q><F><S><D><V><E><E><N><R><T><E><A><P><E><G><T><E><S><E><M><E><T><P><S><A><I><N><G><N><P><S><W><H><L><A><D><S><P><A><V><N><G><A><T><G><H><S><S><S><L><D><A><R><E><V><I><P><M><A><A><V><K><Q><A><L><R><E><A><G><D><E><F><E><L><R><Y><R><R><A><F><S><D... | Isoform Bcl-X(S) promotes apoptosis.<BOP> | Q07817 |
Q96C28 | ZN707_HUMAN | Zinc finger protein 707 | Homo | <M><D><M><A><Q><E><P><V><T><F><R><D><V><A><I><Y><F><S><R><E><E><W><A><C><L><E><P><S><Q><R><A><L><Y><R><D><V><M><L><D><N><F><S><S><V><A><A><L><G><F><C><S><P><R><P><D><L><V><S><R><L><E><Q><W><E><E><P><W><V><E><D><R><E><R><P><E><F><Q><A><V><Q><R><G><P><R><P><G><A><R><K><S><A><D><P><K><R><P><C><D><H><P><A><W><A><H><K><K><T... | May be involved in transcriptional regulation.<BOP> | Q96C28 |
Q9HAT2 | SIAE_HUMAN | Sialic acid-specific 9-O-acetylesterase | Homo | <M><V><A><P><G><L><V><L><G><L><V><L><P><L><I><L><W><A><D><R><S><A><G><I><G><F><R><F><A><S><Y><I><N><N><D><M><V><L><Q><K><E><P><A><G><A><V><I><W><G><F><G><T><P><G><A><T><V><T><V><T><L><R><Q><G><Q><E><T><I><M><K><K><V><T><S><V><K><A><H><S><D><T><W><M><V><V><L><D><P><M><K><P><G><G><P><F><E><V><M><A><Q><Q><T><L><E><K><I><N... | Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid.<BOP> | Q9HAT2 |
Q9BXF6 | RFIP5_HUMAN | Rab11-interacting protein Rip11 | Homo | <M><A><L><V><R><G><A><E><P><A><A><G><P><S><R><W><L><P><T><H><V><Q><V><T><V><L><R><A><R><G><L><R><G><K><S><S><G><A><G><S><T><S><D><A><Y><T><V><I><Q><V><G><R><E><K><Y><S><T><S><V><V><E><K><T><H><G><C><P><E><W><R><E><E><C><S><F><E><L><P><P><G><A><L><D><G><L><L><R><A><Q><E><A><D><A><G><P><A><P><W><A><A><S><S><A><A><A><C><E... | Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.<BOP> | Q9BXF6 |
Q9H343 | O51I1_HUMAN | Olfactory receptor OR11-39 | Homo | <M><L><G><L><N><G><T><P><F><Q><P><A><T><L><Q><L><T><G><I><P><G><I><Q><T><G><L><T><W><V><A><L><I><F><C><I><L><Y><M><I><S><I><V><G><N><L><S><I><L><T><L><V><F><W><E><P><A><L><H><Q><P><M><Y><Y><F><L><S><M><L><A><L><N><D><L><G><V><S><F><S><T><L><P><T><V><I><S><T><F><C><F><N><Y><N><H><V><A><F><N><A><C><L><V><Q><M><F><F><I><H... | Odorant receptor.<BOP> | Q9H343 |
Q7LFX5 | CHSTF_HUMAN | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase | Homo | <M><R><H><C><I><N><C><C><I><Q><L><L><P><D><G><A><H><K><Q><Q><V><N><C><Q><G><G><P><H><H><G><H><Q><A><C><P><T><C><K><G><E><N><K><I><L><F><R><V><D><S><K><Q><M><N><L><L><A><V><L><E><V><R><T><E><G><N><E><N><W><G><G><F><L><R><F><K><K><G><K><R><C><S><L><V><F><G><L><I><I><M><T><L><V><M><A><S><Y><I><L><S><G><A><H><Q><E><L><L><I... | Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequ... | Q7LFX5 |
Q9H5J4 | ELOV6_HUMAN | Very long chain 3-oxoacyl-CoA synthase 6 | Homo | <M><N><M><S><V><L><T><L><Q><E><Y><E><F><E><K><Q><F><N><E><N><E><A><I><Q><W><M><Q><E><N><W><K><K><S><F><L><F><S><A><L><Y><A><A><F><I><F><G><G><R><H><L><M><N><K><R><A><K><F><E><L><R><K><P><L><V><L><W><S><L><T><L><A><V><F><S><I><F><G><A><L><R><T><G><A><Y><M><V><Y><I><L><M><T><K><G><L><K><Q><S><V><C><D><Q><G><F><Y><N><G><P... | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates... | Q9H5J4 |
P85298 | RHG08_HUMAN | Rho-type GTPase-activating protein 8 | Homo | <M><A><G><Q><D><P><A><L><S><T><S><H><P><F><Y><D><V><A><R><H><G><I><L><Q><V><A><G><D><D><R><F><G><R><R><V><V><T><F><S><C><C><R><M><P><P><S><H><E><L><D><H><Q><R><L><L><E><Y><L><K><Y><T><L><D><Q><Y><V><E><N><D><Y><T><I><V><Y><F><H><Y><G><L><N><S><R><N><K><P><S><L><G><W><L><Q><S><A><Y><K><E><F><D><R><K><D><G><D><L><T><M><W... | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.<BOP> | P85298 |
Q96JF0 | SIAT2_HUMAN | Sialyltransferase 2 | Homo | <M><K><P><H><L><K><Q><W><R><Q><R><M><L><F><G><I><F><A><W><G><L><L><F><L><L><I><F><I><Y><F><T><D><S><N><P><A><E><P><V><P><S><S><L><S><F><L><E><T><R><R><L><L><P><V><Q><G><K><Q><R><A><I><M><G><A><A><H><E><P><S><P><P><G><G><L><D><A><R><Q><A><L><P><R><A><H><P><A><G><S><F><H><A><G><P><G><D><L><Q><K><W><A><Q><S><Q><D><G><F><E... | Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycopr... | Q96JF0 |
Q96GS4 | BORC6_HUMAN | Lysosome-dispersing protein | Homo | <M><E><S><S><R><G><R><P><G><P><E><T><D><L><L><A><V><A><E><H><Q><A><L><V><F><G><G><G><P><G><R><T><S><S><E><P><P><A><G><L><R><V><S><G><E><E><E><T><E><N><V><G><G><A><N><R><H><P><R><T><S><P><K><T><S><S><C><G><V><V><H><R><P><E><R><E><A><L><E><N><E><P><G><P><Q><G><T><L><S><G><A><G><S><R><R><G><A><P><G><A><E><H><E><P><S><L><S... | As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.<BOP> | Q96GS4 |
O95264 | 5HT3B_HUMAN | Serotonin receptor 3B | Homo | <M><L><S><S><V><M><A><P><L><W><A><C><I><L><V><A><A><G><I><L><A><T><D><T><H><H><P><Q><D><S><A><L><Y><H><L><S><K><Q><L><L><Q><K><Y><H><K><E><V><R><P><V><Y><N><W><T><K><A><T><T><V><Y><L><D><L><F><V><H><A><I><L><D><V><D><A><E><N><Q><I><L><K><T><S><V><W><Y><Q><E><V><W><N><D><E><F><L><S><W><N><S><S><M><F><D><E><I><R><E><I><S... | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively ... | O95264 |
Q9NUP1 | BL1S4_HUMAN | Protein cappuccino homolog | Homo | <M><E><G><S><F><S><D><G><G><A><L><P><E><G><L><A><E><E><A><E><P><Q><G><A><A><W><S><G><D><S><G><T><V><S><Q><S><H><S><S><A><S><G><P><W><E><D><E><G><A><E><D><G><A><P><G><R><D><L><P><L><L><R><R><A><A><A><G><Y><A><A><C><L><L><P><G><A><G><A><R><P><E><V><E><A><L><D><A><S><L><E><D><L><L><T><R><V><D><E><F><V><G><M><L><D><M><L><R... | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery ... | Q9NUP1 |
Q92520 | FAM3C_HUMAN | Interleukin-like EMT inducer | Homo | <M><R><V><A><G><A><A><K><L><V><V><A><V><A><V><F><L><L><T><F><Y><V><I><S><Q><V><F><E><I><K><M><D><A><S><L><G><N><L><F><A><R><S><A><L><D><T><A><A><R><S><T><K><P><P><R><Y><K><C><G><I><S><K><A><C><P><E><K><H><F><A><F><K><M><A><S><G><A><A><N><V><V><G><P><K><I><C><L><E><D><N><V><L><M><S><G><V><K><N><N><V><G><R><G><I><N><V><A... | May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition.<BOP> | Q92520 |
A0A075B6X5 | TVA18_HUMAN | T cell receptor alpha variable 18 | Homo | <M><L><S><A><S><C><S><G><L><V><I><L><L><I><F><R><R><T><S><G><D><S><V><T><Q><T><E><G><P><V><T><L><P><E><R><A><A><L><T><L><N><C><T><Y><Q><S><S><Y><S><T><F><L><F><W><Y><V><Q><Y><L><N><K><E><P><E><L><L><L><K><S><S><E><N><Q><E><T><D><S><R><G><F><Q><A><S><P><I><K><S><D><S><S><F><H><L><E><K><P><S><V><Q><L><S><D><S><A><V><Y><Y... | V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (... | A0A075B6X5 |
P49959 | MRE11_HUMAN | Meiotic recombination 11 homolog A | Homo | <M><S><T><A><D><A><L><D><D><E><N><T><F><K><I><L><V><A><T><D><I><H><L><G><F><M><E><K><D><A><V><R><G><N><D><T><F><V><T><L><D><E><I><L><R><L><A><Q><E><N><E><V><D><F><I><L><L><G><G><D><L><F><H><E><N><K><P><S><R><K><T><L><H><T><C><L><E><L><L><R><K><Y><C><M><G><D><R><P><V><Q><F><E><I><L><S><D><Q><S><V><N><F><G><F><S><K><F><P... | Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis . The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11 . RAD50 may be req... | P49959 |
Q96S96 | PEBP4_HUMAN | Protein cousin-of-RKIP 1 | Homo | <M><G><W><T><M><R><L><V><T><A><A><L><L><L><G><L><M><M><V><V><T><G><D><E><D><E><N><S><P><C><A><H><E><A><L><L><D><E><D><T><L><F><C><Q><G><L><E><V><F><Y><P><E><L><G><N><I><G><C><K><V><V><P><D><C><N><N><Y><R><Q><K><I><T><S><W><M><E><P><I><V><K><F><P><G><A><V><D><G><A><T><Y><I><L><V><M><V><D><P><D><A><P><S><R><A><E><P><R><Q... | Promotes AKT phosphorylation, suggesting a possible role in the PI3K-AKT signaling pathway.<BOP> | Q96S96 |
Q99679 | GPR21_HUMAN | Probable G-protein coupled receptor 21 | Homo | <M><N><S><T><L><D><G><N><Q><S><S><H><P><F><C><L><L><A><F><G><Y><L><E><T><V><N><F><C><L><L><E><V><L><I><I><V><F><L><T><V><L><I><I><S><G><N><I><I><V><I><F><V><F><H><C><A><P><L><L><N><H><H><T><T><S><Y><F><I><Q><T><M><A><Y><A><D><L><F><V><G><V><S><C><V><V><P><S><L><S><L><L><H><H><P><L><P><V><E><E><S><L><T><C><Q><I><F><G><F... | Orphan receptor.<BOP> | Q99679 |
P47914 | RL29_HUMAN | Large ribosomal subunit protein eL29 | Homo | <M><A><K><S><K><N><H><T><T><H><N><Q><S><R><K><W><H><R><N><G><I><K><K><P><R><S><Q><R><Y><E><S><L><K><G><V><D><P><K><F><L><R><N><M><R><F><A><K><K><H><N><K><K><G><L><K><K><M><Q><A><N><N><A><K><A><M><S><A><R><A><E><A><I><K><A><L><V><K><P><K><E><V><K><P><K><I><P><K><G><V><S><R><K><L><D><R><L><A><Y><I><A><H><P><K><L><G><K><R... | Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell .<BOP> | P47914 |
Q9Y6G9 | DC1L1_HUMAN | Dynein light intermediate chain 1, cytosolic | Homo | <M><A><A><V><G><R><V><G><S><F><G><S><S><P><P><G><L><S><S><T><Y><T><G><G><P><L><G><N><E><I><A><S><G><N><G><G><A><A><A><G><D><D><E><D><G><Q><N><L><W><S><C><I><L><S><E><V><S><T><R><S><R><S><K><L><P><A><G><K><N><V><L><L><L><G><E><D><G><A><G><K><T><S><L><I><R><K><I><Q><G><I><E><E><Y><K><K><G><R><G><L><E><Y><L><Y><L><N><V><H... | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along... | Q9Y6G9 |
Q8N684 | CPSF7_HUMAN | Pre-mRNA cleavage factor Im 59 kDa subunit | Homo | <M><S><E><G><V><D><L><I><D><I><Y><A><D><E><E><F><N><Q><D><P><E><F><N><N><T><D><Q><I><D><L><Y><D><D><V><L><T><A><T><S><Q><P><S><D><D><R><S><S><S><T><E><P><P><P><P><V><R><Q><E><P><S><P><K><P><N><N><K><T><P><A><I><L><Y><T><Y><S><G><L><R><N><R><R><A><A><V><Y><V><G><S><F><S><W><W><T><T><D><Q><Q><L><I><Q><V><I><R><S><I><G><V... | Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs . CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so ... | Q8N684 |
Q8N5M9 | JAGN1_HUMAN | Protein jagunal homolog 1 | Homo | <M><A><S><R><A><G><P><R><A><A><G><T><D><G><S><D><F><Q><H><R><E><R><V><A><M><H><Y><Q><M><S><V><T><L><K><Y><E><I><K><K><L><I><Y><V><H><L><V><I><W><L><L><L><V><A><K><M><S><V><G><H><L><R><L><L><S><H><D><Q><V><A><M><P><Y><Q><W><E><Y><P><Y><L><L><S><I><L><P><S><L><L><G><L><L><S><F><P><R><N><N><I><S><Y><L><V><L><S><M><I><S><M... | Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, ... | Q8N5M9 |
Q8WVK2 | SNR27_HUMAN | U4/U6.U5 tri-snRNP-associated protein 3 | Homo | <M><G><R><S><R><S><R><S><P><R><R><E><R><R><R><S><R><S><T><S><R><E><R><E><R><R><R><R><E><R><S><R><S><R><E><R><D><R><R><R><S><R><S><R><S><P><H><R><R><R><S><R><S><P><R><R><H><R><S><T><S><P><S><P><S><R><L><K><E><R><R><D><E><E><K><K><E><T><K><E><T><K><S><K><E><R><Q><I><T><E><E><D><L><E><G><K><T><E><E><E><I><E><M><M><K><L><M... | May play a role in mRNA splicing.<BOP> | Q8WVK2 |
P43631 | KI2S2_HUMAN | p58 natural killer cell receptor clone CL-49 | Homo | <M><S><L><M><V><V><S><M><A><C><V><G><F><F><L><L><Q><G><A><W><P><H><E><G><V><H><R><K><P><S><L><L><A><H><P><G><P><L><V><K><S><E><E><T><V><I><L><Q><C><W><S><D><V><R><F><E><H><F><L><L><H><R><E><G><K><Y><K><D><T><L><H><L><I><G><E><H><H><D><G><V><S><K><A><N><F><S><I><G><P><M><M><Q><D><L><A><G><T><Y><R><C><Y><G><S><V><T><H><S... | Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.<BOP> | P43631 |
O15442 | MPPD1_HUMAN | Adult brain protein 239 | Homo | <M><W><R><S><R><W><D><A><S><V><L><K><A><E><A><L><A><L><L><P><C><G><L><G><M><A><F><S><Q><S><H><V><M><A><A><R><R><H><Q><H><S><R><L><I><I><E><V><D><E><Y><S><S><N><P><T><Q><A><F><T><F><Y><N><I><N><Q><G><R><F><Q><P><P><H><V><Q><M><V><D><P><V><P><H><D><A><P><K><P><P><G><Y><T><R><F><V><C><V><S><D><T><H><S><R><T><D><P><I><Q><M... | May have metallophosphoesterase activity (in vitro).<BOP> | O15442 |
Q96QF0 | RAB3I_HUMAN | SSX2-interacting protein | Homo | <M><G><L><K><K><M><K><G><L><S><Y><D><E><A><F><A><M><A><N><D><P><L><E><G><F><H><E><V><N><L><A><S><P><T><S><P><D><L><L><G><V><Y><E><S><G><T><Q><E><Q><T><T><S><P><S><V><I><Y><R><P><H><P><S><A><L><S><S><V><P><I><Q><A><N><A><L><D><V><S><E><L><P><T><Q><P><V><Y><S><S><P><R><R><L><N><C><A><E><I><S><S><I><S><F><H><V><T><D><P><A... | Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B . Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form . Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5 . Modulates actin organization and promotes polariz... | Q96QF0 |
Q96F44 | TRI11_HUMAN | Tripartite motif-containing protein 11 | Homo | <M><A><A><P><D><L><S><T><N><L><Q><E><E><A><T><C><A><I><C><L><D><Y><F><T><D><P><V><M><T><D><C><G><H><N><F><C><R><E><C><I><R><R><C><W><G><Q><P><E><G><P><Y><A><C><P><E><C><R><E><L><S><P><Q><R><N><L><R><P><N><R><P><L><A><K><M><A><E><M><A><R><R><L><H><P><P><S><P><V><P><Q><G><V><C><P><A><H><R><E><P><L><A><A><F><C><G><D><E><L... | E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcr... | Q96F44 |
Q8N5F7 | NKAP_HUMAN | NF-kappa-B-activating protein | Homo | <M><A><P><V><S><G><S><R><S><P><D><R><E><A><S><G><S><G><G><R><R><R><S><S><S><K><S><P><K><P><S><K><S><A><R><S><P><R><G><R><R><S><R><S><H><S><C><S><R><S><G><D><R><N><G><L><T><H><Q><L><G><G><L><S><Q><G><S><R><N><Q><S><Y><R><S><R><S><R><S><R><S><R><E><R><P><S><A><P><R><G><I><P><F><A><S><A><S><S><S><V><Y><Y><G><S><Y><S><R><P... | Acts as a transcriptional repressor . Plays a role as a transcriptional corepressor of the Notch-mediated signaling required for T-cell development . Also involved in the TNF and IL-1 induced NF-kappa-B activation. Associates with chromatin at the Notch-regulated SKP2 promoter.<BOP> | Q8N5F7 |
P01717 | LV325_HUMAN | Ig lambda chain V-IV region Hil | Homo | <M><A><W><I><P><L><L><L><P><L><L><T><L><C><T><G><S><E><A><S><Y><E><L><T><Q><P><P><S><V><S><V><S><P><G><Q><T><A><R><I><T><C><S><G><D><A><L><P><K><Q><Y><A><Y><W><Y><Q><Q><K><P><G><Q><A><P><V><L><V><I><Y><K><D><S><E><R><P><S><G><I><P><E><R><F><S><G><S><S><S><G><T><T><V><T><L><T><I><S><G><V><Q><A><E><D><E><A><D><Y><Y><C><Q... | V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep... | P01717 |
Q9BSG1 | ZNF2_HUMAN | Zinc finger protein 661 | Homo | <M><A><A><V><S><P><T><T><R><C><Q><E><S><V><T><F><E><D><V><A><V><V><F><T><D><E><E><W><S><R><L><V><P><I><Q><R><D><L><Y><K><E><V><M><L><E><N><Y><N><S><I><V><S><L><G><L><P><V><P><Q><P><D><V><I><F><Q><L><K><R><G><D><K><P><W><M><V><D><L><H><G><S><E><E><R><E><W><P><E><S><V><S><L><D><W><E><T><K><P><E><I><H><D><A><S><D><K><K><S... | May be involved in transcriptional regulation.<BOP> | Q9BSG1 |
O14653 | GOSR2_HUMAN | Membrin | Homo | <M><D><P><L><F><Q><Q><T><H><K><Q><V><H><E><I><Q><S><C><M><G><R><L><E><T><A><D><K><Q><S><V><H><I><V><E><N><E><I><Q><A><S><I><D><Q><I><F><S><R><L><E><R><L><E><I><L><S><S><K><E><P><P><N><K><R><Q><N><A><R><L><R><V><D><Q><L><K><Y><D><V><Q><H><L><Q><T><A><L><R><N><F><Q><H><R><R><H><A><R><E><Q><Q><E><R><Q><R><E><E><L><L><S><R... | Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.<BOP> | O14653 |
Q96AJ1 | CLUA1_HUMAN | Qilin | Homo | <M><S><F><R><D><L><R><N><F><T><E><M><M><R><A><L><G><Y><P><R><H><I><S><M><E><N><F><R><T><P><N><F><G><L><V><S><E><V><L><L><W><L><V><K><R><Y><E><P><Q><T><D><I><P><P><D><V><D><T><E><Q><D><R><V><F><F><I><K><A><I><A><Q><F><M><A><T><K><A><H><I><K><L><N><T><K><K><L><Y><Q><A><D><G><Y><A><V><K><E><L><L><K><I><T><S><V><L><Y><N><A... | Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling.<BOP> | Q96AJ1 |
O75817 | POP7_HUMAN | Ribonucleases P/MRP protein subunit POP7 homolog | Homo | <M><A><E><N><R><E><P><R><G><A><V><E><A><E><L><D><P><V><E><Y><T><L><R><K><R><L><P><S><R><L><P><R><R><P><N><D><I><Y><V><N><M><K><T><D><F><K><A><Q><L><A><R><C><Q><K><L><L><D><G><G><A><R><G><Q><N><A><C><S><E><I><Y><I><H><G><L><G><L><A><I><N><R><A><I><N><I><A><L><Q><L><Q><A><G><S><F><G><S><L><Q><V><A><A><N><T><S><T><V><E><L... | Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends . Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences .<BOP> | O75817 |
Q8IZ69 | TRM2A_HUMAN | mRNA (uracil-5-)-methyltransferase TRMT2A | Homo | <M><S><E><N><L><D><N><E><G><P><K><P><M><E><S><C><G><Q><E><S><S><S><A><L><S><C><P><T><V><S><V><P><P><A><A><P><A><A><L><E><E><V><E><K><E><G><A><G><A><A><T><G><P><G><P><Q><P><G><L><Y><S><Y><I><R><D><D><L><F><T><S><E><I><F><K><L><E><L><Q><N><V><P><R><H><A><S><F><S><D><V><R><R><F><L><G><R><F><G><L><Q><P><H><K><T><K><L><F><G... | S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine in tRNAs and some mRNAs . Mainly catalyzes the methylation of uridine at position 54 (m5U54) in cytosolic tRNAs . Also able to mediate the formation of 5-methyl-uridine in some mRNAs .<BOP> | Q8IZ69 |
Q9UHR5 | S30BP_HUMAN | Transcriptional regulator protein HCNGP | Homo | <M><A><G><K><K><N><V><L><S><S><L><A><V><Y><A><E><D><S><E><P><E><S><D><G><E><A><G><I><E><A><V><G><S><A><A><E><E><K><G><G><L><V><S><D><A><Y><G><E><D><D><F><S><R><L><G><G><D><E><D><G><Y><E><E><E><E><D><E><N><S><R><Q><S><E><D><D><D><S><E><T><E><K><P><E><A><D><D><P><K><D><N><T><E><A><E><K><R><D><P><Q><E><L><V><A><S><F><S><E... | (Microbial infection) Involved in transcriptional repression of HHV-1 genes TK and gC.<BOP> | Q9UHR5 |
Q969Y2 | GTPB3_HUMAN | Mitochondrial GTP-binding protein 1 | Homo | <M><W><R><G><L><W><T><L><A><A><Q><A><A><R><G><P><R><R><L><C><T><R><R><S><S><G><A><P><A><P><G><S><G><A><T><I><F><A><L><S><S><G><Q><G><R><C><G><I><A><V><I><R><T><S><G><P><A><S><G><H><A><L><R><I><L><T><A><P><R><D><L><P><L><A><R><H><A><S><L><R><L><L><S><D><P><R><S><G><E><P><L><D><R><A><L><V><L><W><F><P><G><P><Q><S><F><T><G... | GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.<BOP> | Q969Y2 |
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